research Role of -catenin in Epidermal Stem Cell Expansion, Lineage Selection, and Cancer
Beta-catenin is crucial for skin cell growth, development, and cancer formation.
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30 / 1000+ results research The Vitamin D Receptor Is Required for Mouse Hair Cycle Progression but not for Maintenance of the Epidermal Stem Cell Compartment
Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.
research A Niche Above: A Novel Modality of Stem Cell Regulation in Mammalian Skin Epidermis
Skin cell behavior is influenced by the tightness of nearby cells, affecting their growth and development.
research Lineage Analysis of Epidermal Stem Cells
Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
research Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity
Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.
research Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages
Epidermal β-catenin activation changes the dermis by signaling different fibroblast types.
research Epidermal pigmentation in the human lineage is an adaptation to ultraviolet radiation
Forensic DNA Phenotyping can help predict physical traits from crime scene DNA to identify suspects.
research Epidermal stem cell diversity and quiescence
Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
research Dermal niche signaling and epidermal stem cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Developing stratified epithelia: lessons from the epidermis and thymus
The skin and thymus develop similarly to protect and support immunity.
research Differentiation of Mouse Induced Pluripotent Stem Cells into a Multipotent Keratinocyte Lineage
Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.
research Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence
Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
research Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell?
New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
research JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin
JunB is crucial for maintaining healthy skin and hair follicles.
research Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis
A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.
research Epidermal stem cell lineages
Epidermal stem cells are crucial for skin health and problems with them can cause issues like poor wound healing, cancer, and aging.
research Basal cells in the epidermis and epidermal differentiation
The exact identity of skin stem cells and how skin cells differentiate is not fully known.
research Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin
Tcf3 and Lef1 are key in deciding skin stem cell roles.
research Tenascin-C expressing touch dome keratinocytes exhibit characteristics of all epidermal lineages
Touch dome keratinocytes in adult skin have traits of different skin cell types.
research Human skin stem cells and the ageing process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Neuregulin3 alters cell fate in the epidermis and mammary gland
Neuregulin3 affects cell development in the skin and mammary glands.
research Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment
Myc activation reduces skin stem cells by affecting cell adhesion.
research Mediator 1 ablation induces enamel-to-hair lineage conversion in mice through enhancer dynamics
Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.
research Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties
Wounded skin cells can revert to stem cells and help heal.
research Multi-potentiality of a new immortalized epithelial stem cell line derived from human hair follicles
Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.
research Characterisation of CD4+ stem cells of the skin and their role in skin homeostasis and tumourigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors
Fibroblasts can be turned into melanocytes for potential skin treatments.
research The Mixed Lineage Kinase Leucine-Zipper Protein Kinase Exhibits a Differentiation-Associated Localization in Normal Human Skin and Induces Keratinocyte Differentiation upon Overexpression
ZPK helps skin cells mature and may affect skin health.
research Hair follicle epithelial stem cells contribute to interfollicular epidermis during homeostasis
Hair follicle stem cells help maintain skin health by moving to and supporting the skin's surface layers.
research Hair follicle stem cell progeny heal blisters while pausing skin development
Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.