research Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation
mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.
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30 / 1000+ resultsresearch 732 Ceramide synthase 4 controls epidermal lipid composition and barrier function
Ceramide synthase 4 is essential for maintaining skin barrier health.
research A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity
Keratin is crucial for skin barrier formation and affects mitochondrial function.
research Obesity resistance of the stearoyl-CoA desaturase-deficient (scd1 -/-) mouse results from disruption of the epidermal lipid barrier and adaptive thermoregulation
Deleting the scd1 gene in mice prevents obesity by disrupting skin lipids and improving heat regulation.
research The lipide composition of epidermis and dermis of mice undergoing carcinogenesis by methylcholanthrene.
Cholesterol and phospholipids increase in mouse skin during cancer development, with differences between male and female skin.
research Einfluss des Lipidmusters und der Morphologie der Epidermis auf transdermale Permeationsraten im In-vitro-Versuch
Porcine skin is a good substitute for human skin in drug diffusion tests.
research Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting
P-SLN nanoparticles effectively deliver podophyllotoxin to the skin.
research Influence of Hair Growth Cycle on Lipid Composition of Mouse Epidermis and Dermis.
Hair growth stages don't significantly change lipid content in mouse skin.
research Influence of Sex and Hair Growth Cycle on Lipid Composition of Mouse Epidermis.
Male and female mice have different lipid compositions in their skin during hair growth cycles.
research In Vitro, Ex Vivo, Penetration (EpiDermTM) and in Vivo Dermatokinetics of Ketoconazole Loaded Solid Lipid Nanoparticles for Topical Delivery
Ketoconazole loaded solid lipid nanoparticles can penetrate skin better than regular drug suspension and marketed product, providing slow, sustained release and improved stability.
research Integral hair lipid in human hair follicle
Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.
research Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis
Skin acetyl-CoA synthesis is crucial for overall lipid balance.
research Lipid nanoparticles for topical and transdermal delivery of pharmaceuticals and cosmeceuticals
Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.
research Epidermal Barrier
Healthy skin prevents water loss and protects against threats.
research Integral Lipid in Human Hair Follicle
The lipid in human hair follicles acts as a barrier, similar to the skin's lipid layer.
research Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency
Fatp4 is crucial for healthy skin development and function.
research Sebaceous lipids are essential for water repulsion, protection against UVB-induced apoptosis, and ocular integrity in mice
Sebaceous lipids are crucial for keeping skin and eyes healthy in mice.
research Hair Growth Cycle Is Arrested in SCD1 Deficiency by Impaired Wnt3a-Palmitoleoylation and Retrieved by the Artificial Lipid Barrier
An artificial lipid barrier can restore hair growth in cases of SCD1 deficiency.
research Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids
The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.
research 090 Reactive lipids from the secretome of senescent fibroblasts modify the extracellular matrix with functional consequences for resident cells
Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.
research Does dry skin indicate defective epidermal permeability barrier?
Dry skin does not mean the skin's protective barrier is broken; it's often due to a lack of natural skin moisturizers.
research Loss of ERBB2 and ERBB3 Receptors Impacts Epidermal Differentiation in Mice
Losing both ERBB2 and ERBB3 receptors in mice causes significant skin problems and inflammation.
research The dark and the bright sides of the transcription factor Nrf2 in skin protection and disease (Nrf2 and epidermal barrier function)
Nrf2 helps protect skin from damage but too much can cause skin problems.
research Dietary lipids are largely deposited in skin and rapidly affect insulating properties
Dietary fats are stored in the skin, affecting body heat regulation.
research SOLID LIPID NANOPARTICLES OF FENUGREEK SEED EXTRACT IN A DERMATOLOGICAL BASE FOR ALOPECIA: AN IN VIVO STUDY
Fenugreek seed extract in nanoparticles effectively promotes hair growth.
research Regulation of epidermal proliferation and hair follicle cycling by synthetic photostable retinoid EC23
The synthetic retinoid EC23 thickens skin and promotes hair growth more effectively and with a lower dose than natural retinoids.
research Beauty is skin deep: the fascinating biology of the epidermis and its appendages.
The biology of skin and hair is complex and not fully understood.
research JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin
JunB is crucial for maintaining healthy skin and hair follicles.
research Phospholipase A2 in skin biology: new insights from gene-manipulated mice and lipidomics
Phospholipase A2 enzymes play key roles in skin health and disease.
research TCF/Lef1-Mediated Control of Lipid Metabolism Regulates Skin Barrier Function
TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.