research Hair follicle stem cell progeny heal blisters while pausing skin development
Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.
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research Influence of donor sources and culture media on the histo-morphological quality of human artificial skin models
EpiLife® media and younger donor age improve artificial skin model quality.
research Trichoscopy
Trichoscopy is a useful tool for diagnosing different hair and scalp diseases without surgery.
research Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22
miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.
research Identifying molecular targets for reverse aging using integrated network analysis of transcriptomic and epigenomic changes during aging
Curcumin may help reverse aging by targeting specific genes.
research Developing human fetal skin demonstrates a unique lymphocyte signature
Fetal skin has unique immune cells different from adult skin.
research Glutamate transporter Slc1a3 mediates inter‐niche stem cell activation during skin growth
The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
research The therapeutic promise of apoptosis
Blocking cell death in certain stem cells can improve wound healing and tissue regeneration.
research Araliadiol Protects Human Keratinocytes From Oxidative Stress, DNA Damage, and Apoptosis via Activation of Antioxidant Signaling
Araliadiol protects skin cells from damage by boosting antioxidant defenses.
research In vitro skin models to study epithelial regeneration from the hair follicle
PSU are better than THF at regenerating skin layers in lab models.
research Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine
Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
research Understanding Cancer Cells of Origin in Cutaneous Tumors
The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.
research Noval advance of histone modification in inflammatory skin diseases and related treatment methods
Histone modification is key in treating chronic inflammatory skin diseases.
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research Identification of the cell lineage at the origin of basal cell carcinoma
Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
research Comparative transcriptomic analysis of dermal wound healing reveals de novo skeletal muscle regeneration in Acomys cahirinus
The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.
research Protection against chemotherapy-induced alopecia: targeting ATP-binding cassette transporters in the hair follicle?
Increasing ABC transporters in hair follicles may prevent chemotherapy-induced hair loss.
research Natural Skin Whitening Compounds: Types, Source and Mechanism of Action: A Review
Natural compounds can lighten skin by reducing melanin.
research The role of lymphocytes in the development and treatment of alopecia areata
Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
research The Overexpression of Tβ4 in the Hair Follicle Tissue of Alpas Cashmere Goats Increases Cashmere Yield and Promotes Hair Follicle Development
Overexpressing Tβ4 in goats' hair follicles increases cashmere production and hair follicle growth.
research Requirement of zinc transporter ZIP10 for epidermal development: Implication of the ZIP10–p63 axis in epithelial homeostasis
ZIP10 is crucial for skin development and maintaining healthy skin.
research Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors
Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.
research Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer
The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
research Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis
HDAC1 is crucial for skin development and preventing tumors.
research Regulatory T cells in skin regeneration and wound healing
Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.
research Author response: Hair follicle epidermal stem cells define a niche for tactile sensation
Skin stem cells in hair follicles are important for touch sensation.
research Decision letter: Hair follicle epidermal stem cells define a niche for tactile sensation
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
research Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells
Wnt signaling is crucial for skin development and hair growth.
research Conditional Knockout in Mice Reveals the Critical Roles of Ppp2ca in Epidermis Development
PP2Acα is essential for proper hair and skin development.
research Human Regulatory T Cells: Understanding the Role of Tregs in Select Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers
Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.