research Activity evaluation of epidermo-melanin unit and dermal damage in melasma
Melasma results from changes in the skin's pigment and structure, not just pigment cell growth.
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research Melasma in Men
Treating melasma in men is difficult, especially for the deeper skin layers, and may need more than just topical treatments.
research Major approaches of molecular and physiopathological mechanisms for hormonal treatment of melasma: a systematic review
Estrogens and progesterone are key in regulating melasma pigmentation.
research 43225 Randomized study to assess the efficacy of a facial cosmetic product with nanoencapsulated cysteamine in women presenting melasma
The cosmetic product improved melasma and skin quality without causing irritation.
research Histological features of melasma lesions and the expression of keratin 10
Melasma skin has more melanin and signs of aging, with strong CK10 expression linked to cell differentiation and aging.
research Treatment with injectable platelet-rich fibrin in a rat model of melasma
Injectable platelet-rich fibrin can safely and effectively treat melasma.
research Dermaroller in dermatology and cosmetology
Dermaroller is effective and safe for improving skin conditions like acne scars and alopecia with minimal side effects.
research Clinical Snippets
New findings suggest potential treatments for melanoma, hyperpigmentation, hair defects, and multiple sclerosis, and show skin microbiome changes don't cause atopic dermatitis.
research Enhanced Differentiation Potential of Pigmented Human Epidermal Equivalents
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
research An Open-Label Comparative Study on the Effects of Platelet-Rich Plasma Therapy with Hydroquinone 4% Versus Hydroquinone 4% Alone in Melasma
Combining PRP with hydroquinone is more effective for treating melasma than using hydroquinone alone.
research Caracterização clínica e laboratorial do acometimento dos folículos velos e da epiderme da face, pescoço e região anterossuperior do tórax na alopecia frontal fibrosante
Alopecia frontal fibrosante affects facial vellus hair and can be diagnosed with dermatoscopy.
research Melasma and Endocrine Disorders
Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.
research BC02 (P80): A systematic review of laser treatment of verrucous epidermal naevi
Laser treatment for skin conditions VEN and ILVEN is effective and liked by patients.
research The association between melasma and iron profile: a case-control study
Lower ferritin and serum iron levels may be linked to melasma.
research The role of microneedling in treatment of melasma
Microneedling may improve melasma treatment by boosting topical therapy effectiveness.
research Clinical and Dermoscopic Evaluation of the Efficacy Melasma Treatment with Oral Tranexamic Acid
Oral tranexamic acid is a safe and effective treatment for melasma.
research Hyperpigmentation and Melasma
Hyperpigmentation is common in pregnancy and may not fully fade after birth; melasma, also frequent, can persist but has limited treatment options during pregnancy.
research Platelet‐rich plasma is a promising therapy for melasma
Platelet-rich plasma therapy could be an effective treatment for melasma with minimal side effects.
research Safety and efficacy of a novel skin lightening agent for melasma
The new treatment was safe and may effectively treat male pattern hair loss.
research Low‐fluence Q‐switched Nd: YAG 1064‐nm laser and intense pulsed light for the treatment of melasma
Combining LFQS and IPL is more effective and faster for treating melasma than LFQS alone.
research Melanin Pigmentary Disorders: Treatment Update
Treatments for melanin disorders exist, but more effective options needed.
research Update on Melasma—Part I: Pathogenesis
Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
research Unmasking Melasma: Confronting the Treatment Challenges
Melasma treatment is difficult, but combination therapies and personalized plans show promise.
research Melasma, a photoaging disorder
Melasma is now considered a skin aging disorder caused by sun exposure in people with a genetic tendency, which impacts treatment and prevention approaches.
research Origin, Clinical Presentation, and Diagnosis of Facial Hypermelanoses
Facial dark spots can be caused by the sun, genetics, makeup, or medicine, and are diagnosed by patient history and skin tests.
research DNA Methyltransferases in Malar Melasma and Their Modification by Sunscreen in Combination with 4% Niacinamide, 0.05% Retinoic Acid, or Placebo
Treatments with sunscreen and active ingredients can reduce skin hyperpigmentation by decreasing DNA methylation.
research Evaluation of Two Medium-Depth Peels: Glycolic Acid 70% Versus Trichloroacetic Acid 35%: A Histological and Immunohistochemichal Study on Rat Skin
Both TCA and GA peels effectively improved skin thickness and collagen without significant differences.
research Melasma and other skin manifestations or oral contraceptives.
Oral contraceptives often cause melasma and other skin issues.
research Liposomes in cosmeceutics
Liposomes could improve how skin care products work but are costly and not very stable.
research Microneedling: Where do we stand now? A systematic review of the literature
Microneedling is a safe and effective treatment for various skin conditions, often preferred for its fewer side effects and shorter recovery time.