70 citations
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November 1984 in “Cell & tissue research/Cell and tissue research” Vitamin D3 affects cell differentiation in specific skin areas.
69 citations
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August 1999 in “Developmental biology” The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
68 citations
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December 1991 in “Annals of the New York Academy of Sciences” Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.
67 citations
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November 2019 in “Nature Communications” Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
67 citations
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June 2019 in “Proceedings of the National Academy of Sciences” A new 3D culture system helps grow and study mouse skin stem cells for a long time.
63 citations
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March 2018 in “Experimental Dermatology” Collagen XVII is vital for skin structure, hair stem cell support, and skin cell regulation.
62 citations
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July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
62 citations
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October 2010 in “Journal of biomedical nanotechnology” Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.
62 citations
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January 2000 in “Developmental dynamics” Notch-related genes play a key role in the development and cycling of hair follicles.
61 citations
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December 2016 in “The EMBO Journal” The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.
59 citations
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June 2023 in “Nature Aging” Blocking IL-17 signaling may reduce skin inflammation and delay aging.
58 citations
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January 2020 in “International Journal of Molecular Sciences” Different methods of preparing Platelet-Rich Plasma (PRP) can affect wound healing and hair regrowth in plastic surgery. Using a kit with specific standards helps isolate PRP that meets quality criteria. Non-Activated PRP and Activated PRP have varying effects depending on the tissue and condition treated. For hair regrowth, Non-Activated PRP increased hair density more than Activated PRP. Both treatments improved various aspects of scalp health.
57 citations
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August 2002 in “American Journal Of Pathology” Cathepsin L deficiency causes hair and skin issues in mice.
57 citations
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February 1994 in “Experimental dermatology” Melatonin affects mouse skin and may regulate skin functions.
53 citations
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July 2009 in “Cancer Research” Blocking certain proteins can reduce skin inflammation caused by cancer treatment.
52 citations
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October 2007 in “Molecular Therapy” Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.
52 citations
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May 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” Parathyroid hormone-related protein helps control hair growth phases in mice.
51 citations
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February 2004 in “Journal of Investigative Dermatology” MCSP may help identify and regulate skin stem cells, affecting hair growth and regeneration.
45 citations
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November 2017 in “Biomaterials” Researchers found a new way to create hair-growing structures in the lab that can grow hair when put into mice.
44 citations
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July 2020 in “Stem Cell Research & Therapy” Epidermal stem cells show promise for skin repair and regeneration.
44 citations
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July 2016 in “Stem Cells Translational Medicine” Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.
44 citations
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December 1991 in “Annals of the New York Academy of Sciences” EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
43 citations
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January 2011 in “Plastic and Reconstructive Surgery” Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.
41 citations
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December 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Deleting MED1 in skin cells causes hair loss and skin changes.
39 citations
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November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Fatp4 is crucial for healthy skin development and function.
39 citations
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October 2010 in “Journal of The American Academy of Dermatology” Some patients with mycosis fungoides or Sézary syndrome experience hair loss, which may be similar to alopecia areata or linked to skin lesions, possibly due to abnormal T cells, and bexarotene can help treat it.
37 citations
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July 2016 in “Current Opinion in Cell Biology” Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
36 citations
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January 2014 in “Elsevier eBooks” The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.
35 citations
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August 2010 in “The American journal of pathology” Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.
34 citations
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June 2008 in “In vitro cellular & developmental biology. Animal” Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.