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June 2016 in “Genesis” Researchers identified specific genes that are important for mouse skin cell development and healing.
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July 2008 in “Acta Biochimica et Biophysica Sinica” Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.
32 citations
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August 2019 in “Nature Communications” Chemotherapy causes permanent hair follicle damage by triggering stem cell loss.
January 2026 in “Frontiers in Pharmacology” Sanhuang Fukang oil helps heal radiation skin injuries by reducing inflammation and cell death.
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May 2012 in “Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism” Human scalp hair follicles can be used to study how prolactin affects hair growth and cell death.
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July 2017 in “Scientific Reports” JMJD3 and NF-κB activate Notch1, which is essential for skin cell movement and wound healing.
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April 2000 in “Gene” Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.
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June 2017 in “Journal of Investigative Dermatology” Blimp1 is crucial for hair follicle growth and skin health.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The article concludes that creating a detailed map of normal human skin at the single-cell level is important.
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March 2015 in “Experimental Dermatology” LHX2 and SOX9 identify unique hair follicle cell groups, crucial for hair maintenance.
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October 2010 in “Journal of Investigative Dermatology” Activating Kras in mouse skin causes excess skin and hair loss.
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February 2018 in “Oncotarget” Lower SMAD2/3 activation predicts more severe skin cancer.
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May 2022 in “Cell Reports” Basal cell carcinomas need extra mutations to grow from small to large tumors.
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May 2024 in “Developmental Cell” Lower GATA3 levels in mice help hair regrow by changing certain immune cells.
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February 2012 in “Journal of Clinical Investigation” Blocking Hedgehog signaling offers new treatment options for advanced basal cell carcinoma.
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September 2010 in “Cancer Prevention Research” Overactive signaling in hair follicles can lead to skin cancer.
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October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
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May 2019 in “Frontiers in Cell and Developmental Biology” Abnormal ECM and immune cell interactions can cause skin diseases.
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November 2023 in “International Journal of Molecular Sciences” Melatonin helps reduce aging signs in human eyelid skin.
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June 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.
January 2024 in “Inflammation and regeneration” Th22 cells are essential for Tβ15-induced hair growth in mice.
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March 2009 in “Dermatology Online Journal” Understanding EGFR roles could lead to new hair loss treatments.
March 2009 in “Dermatology Online Journal” Manipulating EGFR signaling may help treat hair loss and promote hair growth.
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February 2019 in “eLife” BMP signaling is essential for the development of touch domes.
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October 2021 in “Clinical, Cosmetic and Investigational Dermatology” The secretome from mesenchymal stem cells shows promise for treating skin conditions and improving skin and hair health, but more research is needed.
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March 1995 in “Journal of cell science” SV40 T antigen in hair follicles causes abnormal hair and health issues in mice.
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.