Non-immune dermal cells dominate, epidermal cells increase after day 9, and certain immune cells persist beyond inflammation in wound-induced hair follicle regeneration.
October 2018 in “Vestnik dermatologii i venerologii” Certain growth factors affect hair loss in women and could be targeted for treatment.
15 citations
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December 2020 in “The Journal of General Physiology” Acid can block TRPV3 from outside the cell but boost its function from inside.
December 2024 in “Frontiers in Genetics” EGFR and mTOR inhibitors may help manage Olmsted syndrome symptoms.
209 citations
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October 2008 in “The Journal of Pathology” Stem cell niches are essential for tissue health and repair.
26 citations
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December 2020 in “Genes” A combination of IGF-1 and EGF promotes hair growth in Angora rabbits.
23 citations
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May 2023 in “Cell Proliferation” TGF-β and FGF pathways are crucial for skin development and regeneration.
22 citations
,
September 2011 in “Journal of Investigative Dermatology” TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.
6 citations
,
July 2009 in “Journal of Cutaneous Pathology” Hair follicle stem cells are key for hair growth and skin repair.
May 2025 in “Proceedings of the National Academy of Sciences” UTX is crucial for skin differentiation and health, especially in females.
March 2025 in “Journal of Cosmetic Dermatology” Thermus thermophilus extract improves hair growth and scalp health in men with hair loss.
15 citations
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June 2011 in “Journal of Investigative Dermatology” Overexpressing 14-3-3σ in mice skin reduces cell growth and hair density.
May 2007 in “Science's STKE” Healing skin wounds in mice can create new hair follicles, and adjusting Wnt signaling could potentially reduce scarring and treat hair loss.
854 citations
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February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
20 citations
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December 2019 in “International Journal of Molecular Sciences” HB-EGF boosts the hair growth ability of stem cells, making it a potential hair loss treatment.
10 citations
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January 2019 in “International Immunology” Immune cells help keep skin healthy and repair it, but imbalance can cause disease.
7 citations
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February 2023 in “Inflammation and Regeneration” The protein interleukin-1 alpha helps regenerate hair follicles and increase stem cell growth in mice.
January 2025 in “International Journal of Molecular Sciences” Non-liganded Vitamin D Receptor is crucial for healthy skin and hair.
32 citations
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April 2017 in “Scientific Reports” Platelet-rich plasma can help grow more mouse hair follicles, but it doesn't work for human hair follicles yet.
27 citations
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August 2015 in “Experimental Dermatology” Certain electric currents can promote hair growth by activating specific cell pathways.
September 2004 in “Experimental Dermatology” Key signals like Wnt and β-catenin are crucial for skin and hair development, with potential for treating skin disorders.
1 citations
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January 2020 Ift20 is essential for hair follicle function and skin cell movement.
118 citations
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January 2016 in “Current Topics in Developmental Biology” The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
8 citations
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April 2009 in “International journal of oncology” Hair follicle cells resist turning into skin cells.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
April 2017 in “Journal of Investigative Dermatology” Fisetin may help treat psoriasis and reduce skin inflammation.
January 2016 in “Experimental Dermatology” New findings suggest potential treatments for melanoma, hyperpigmentation, hair defects, and multiple sclerosis, and show skin microbiome changes don't cause atopic dermatitis.
133 citations
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February 2019 in “PLoS Biology” Feather patterns in birds are shaped by signaling interactions and cell movements, with EDA/EDAR crucial for pattern formation.
45 citations
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May 2003 in “Journal of Cell Science” α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.
24 citations
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November 2021 in “PLoS ONE” Ablative fractional laser treatment rejuvenates skin by altering gene expression and promoting wound healing and tissue regeneration.