57 citations
,
March 2018 in “International Journal of Molecular Sciences” The extracellular matrix is crucial for controlling skin stem cell behavior and health.
354 citations
,
February 2011 in “Genes & Development” EZH1 and EZH2 are crucial for healthy hair growth and skin repair.
293 citations
,
November 2011 in “Nature” The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.
39 citations
,
March 2009 in “Dermatology Online Journal” Understanding EGFR roles could lead to new hair loss treatments.
32 citations
,
December 2014 in “Cold Spring Harbor Perspectives in Medicine” Disruptions in epidermal polarity genes can lead to skin diseases.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
April 2018 in “Journal of Investigative Dermatology” Ceramide synthase 4 is essential for maintaining skin barrier health.
May 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A balance between BMP and Wnt signals is crucial for hair follicle stem cell function and hair growth.
Type XVII collagen may help prevent skin aging.
61 citations
,
September 2008 in “Stem Cells” Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
51 citations
,
August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
2 citations
,
September 2023 in “International journal of molecular sciences” Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
Mdm2 is crucial for controlling p53 to maintain healthy cells and prevent tumors.
85 citations
,
June 2017 in “Journal of Investigative Dermatology” Blimp1 is crucial for hair follicle growth and skin health.
53 citations
,
February 2015 in “Journal of Investigative Dermatology” Ceramide Synthase 4 is essential for normal hair growth and preventing hair loss.
9 citations
,
November 2013 in “Journal of Investigative Dermatology” Overexpressing CtBP1 in skin cells causes skin and hair problems.
7 citations
,
April 2012 in “Biomolecular concepts” Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
January 2026 in “British Journal of Dermatology” ELF5 is essential for skin cell growth and maintenance.
October 2018 in “Deep Blue (University of Michigan)” Hair follicle development involves specific cells and genes, crucial for understanding severe skin diseases like harlequin ichthyosis.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Esrp1 is important for skin health by helping form and maintain the skin barrier.
July 2016 in “Cancer research” Mutant cells in hair follicles are influenced by their location and interactions with surrounding cells.
9 citations
,
May 2002 in “PubMed” Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.
6 citations
,
October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
January 2025 in “International Journal of Molecular Sciences” Non-liganded Vitamin D Receptor is crucial for healthy skin and hair.
46 citations
,
November 2004 in “Lipids” PPARs help regulate skin health and could be used to treat skin disorders.
January 2025 in “Medical Research Archives” Hair follicles are vital for skin health, cancer prevention, and wound healing.
September 2017 in “Journal of Investigative Dermatology” LRIG1 protein affects hair growth by regulating skin receptors, leading to hair loss when overexpressed.
27 citations
,
May 2024 in “Clinical and Translational Medicine” Melanocyte stem cells are vital for skin and hair color and have potential in treating skin disorders and cancer.
2 citations
,
March 2020 in “Cell” Elaine Fuchs' research shows how skin stem cells maintain health, aid in healing, and are involved in cancer.
84 citations
,
January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” Skin stem cells help maintain skin health, grow hair, and heal wounds.