85 citations
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January 2018 in “Cell stem cell” Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
4 citations
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July 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” BLMP-1 is important for regular molting and gene expression cycles in worms.
47 citations
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July 2023 in “Nature Genetics” 3 citations
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July 2017 in “Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model” Mouse hair follicle stem cells have a flexible chromatin state that supports skin health and hair growth.
23 citations
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March 2023 in “eLife” Stem cell differentiation involves gradual chromatin changes and dynamic gene activity.
December 2025 in “npj Systems Biology and Applications” Cold temperatures can stop human cell circadian rhythms, but warming restores them.
12 citations
,
November 2014 in “PLOS Computational Biology” The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
22 citations
,
June 2017 in “Stem cell reports” PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.
85 citations
,
July 2002 in “Pigment Cell Research” The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
1 citations
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November 2020 in “Biochemical Society transactions” Different types of skin stem cells can change and adapt, which is important for developing new treatments.
July 2025 in “Genome biology” HT-scCAT-seq helps understand gene regulation in embryonic skin development.
January 2022 in “Figshare” Melatonin affects when and how goat hair follicle genes turn on and off during growth cycles.
September 2020 in “Research Square (Research Square)” Goat skin adapts to seasonal changes through genes that respond to daylight length, affecting hormone levels and potentially making skin cells light-sensitive.
January 2022 in “Figshare” Melatonin affects when and how goat hair follicle genes turn on and off during growth cycles.
29 citations
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February 2001 in “Proceedings of the National Academy of Sciences” A specific DNA region controls skin cell gene expression by working with certain proteins.
117 citations
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August 1999 in “Nature Genetics”
January 2022 in “Figshare” Melatonin affects when and how goat hair follicle genes turn on and off during growth cycles.
January 2022 in “Figshare” Melatonin affects when and how goat hair follicle genes turn on and off during growth cycles.
667 citations
,
May 2008 in “Genes & Development” Histone demethylases can change gene expression and may be linked to diseases like cancer.
5 citations
,
November 2020 in “EBioMedicine” Disruptions in sleep-wake cycles can cause health problems like mental, metabolic, and heart diseases, and cancer.
January 2011 in “China Animal Husbandry & Veterinary Medicine” Constant-release melatonin reduces SOX21 gene expression in goats during the hair follicle resting phase.
354 citations
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February 2011 in “Genes & Development” EZH1 and EZH2 are crucial for healthy hair growth and skin repair.
35 citations
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November 2021 in “Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology” DNA methylation changes in Tan sheep affect growth and fur traits.
3 citations
,
January 2023 in “Science advances” The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Key skin cell regulators and gene organization changes are crucial for skin cell development and could help treat skin disorders.
April 2024 in “Communications biology” Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.
January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” DNA methylation controls hair follicle gene expression in cashmere goats.
49 citations
,
March 2017 in “PubMed” Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.
January 2016 in “Xumu Shouyi Xuebao” October 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Genetic manipulations that extend lifespan in mice may not work as effectively in humans.