research Stem cells in tissues, organoids, and cancers
Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
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research TGFβ and cancer metastasis: an inflammation link
TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.
research Curtailing PCOS
Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.
research Desferrioxamine treatment of aceruloplasminemia: Long‐term follow‐up
Finasteride may help reduce symptoms in male Tourette syndrome patients.
research Psoriasis patients demonstrate HLA-Cw*06:02 allele dosage-dependent T cell proliferation when treated with hair follicle-derived keratin 17 protein
Psoriasis patients' immune response to a hair protein depends on their specific gene type.
research Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research Cognitive and mood side effects of lower urinary tract medication
Some medications for bladder problems can cause memory issues or mood changes, and doctors should monitor these side effects.
research An incompletely penetrant novel MAFB (p.Ser56Phe) variant in autosomal dominant multicentric carpotarsal osteolysis syndrome
Researchers found a new gene variant linked to a rare bone disease, which doesn't always cause symptoms in carriers.
research Genetic basis of polycystic ovary syndrome
The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.
research Pathological findings in a case of stiff person syndrome with anti‐GAD antibodies
Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.
research The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development
The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
research The promise and challenges of cell therapy for psoriasis*
Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
research Post-finasteride syndrome
Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.
research Chi-miR-30b-5p inhibits dermal papilla cells proliferation by targeting CaMKIIδ gene in cashmere goat
A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.
research Small Intestinal Organoid-Derived SP Cells Contribute to Repair of Irradiation-Induced Skin Injury
Intestinal stem cells can help repair skin damage from radiation.
research Can plant‐derived phytochemicals provide symptom relief for hair loss? A critical review
Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
research Why were Sardinians the shortest Europeans? A journey through genes, infections, nutrition, and sex
Sardinians were historically short due to a mix of genetics and factors like disease and poor nutrition, but recent height increases suggest better living conditions had a bigger impact.
research Mutation in 5′ upstream region of GCH I gene causes familial dopa-responsive dystonia
A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.
research Ability to cycle despite severe freezing of gait in atypical parkinsonism in Fahr's syndrome
Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.
research Encephalitis lethargica due to Epstein–Barr virus infection
Finasteride may help reduce tic severity in male Tourette syndrome patients.
research Impaired differentiation potential of CD34-positive cells derived from mouse hair follicles after long-term culture
Mouse hair follicle stem cells lose their ability to change into different cell types after being grown for a long time.
research Gonadal Sex Steroids: Production, Action and Interactions in Mammals
The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
research Co-opting Developmental Signaling Pathways to Promote Wound Healing
Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.
research Bridging psychoneuroimmunology and homeopathy: Modulating the cellular and emotional cascades in refractory alopecia
Individualized Homeopathic Medicine shows promise for treating alopecia with lasting hair regrowth.
research SARS-CoV-2 infection reduces the number of spermatogonial stem cells and dysregulates the transcriptional landscape of the human testis
COVID-19 can harm male fertility by reducing sperm stem cells and damaging testicular function.
research A Comprehensive Review of Management of Patients with Infertility having Polycystic Ovarian Syndrome
PCOS-related infertility is managed with lifestyle changes and medications.
research Therapeutic small extracellular vesicles from key human stem and immune cellular sources: A review
Small extracellular vesicles from stem and immune cells show promise for treating various diseases but face challenges in clinical use.
research ラット精巣におけるビタミンD 代謝関連遺伝子の発現解析
The testes significantly contribute to vitamin D metabolism and may affect male reproductive health and conditions like hair loss.
research Adli Uygulamalarda Yeni Nesil Dizileme Teknolojilerinin Yeri ve Önemi
Next-Generation Sequencing improves forensic analysis by providing detailed genetic information quickly.
research KOMÓRKI VSELs KLUCZEM DO DŁUGOWIECZNOŚCI
VSELs may hold the key to longer life through regenerative therapies.