36 citations
,
September 2009 in “Journal of Cellular and Molecular Medicine” New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
33 citations
,
January 2018 in “International Journal of Biological Sciences” CRISPR-Cas9 can successfully edit genes in large mammals like Cashmere goats.
30 citations
,
April 2020 in “Stem Cell Research & Therapy” PI3K/Akt pathway is crucial for hair growth and regeneration.
30 citations
,
April 2017 in “Experimental Dermatology” Hair follicle stem cells and skin cells show promise for hair and skin therapies but need more research for clinical use.
29 citations
,
December 2005 in “BioEssays” Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.
25 citations
,
September 2018 in “Molecular Biology of the Cell” Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
22 citations
,
May 2021 in “Nature Communications” Tissue stiffness affects hair follicle regeneration, and Twist1 is a key regulator.
22 citations
,
June 2013 in “International journal of molecular sciences” Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
21 citations
,
December 2016 in “PLOS ONE” Scientists made skin stem cells from other human cells with over 97% efficiency, which could help treat skin conditions.
19 citations
,
July 2011 in “Microscopy and Microanalysis” The hair follicle bulge is an important area for adult stem cells involved in hair growth and repair, with potential for medical use needing more research.
18 citations
,
December 2020 in “Frontiers in cell and developmental biology” miR-140-5p in certain cell vesicles helps hair growth by boosting cell proliferation.
16 citations
,
March 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
16 citations
,
April 2015 in “Lasers in Surgery and Medicine” Using a fractional laser can stimulate hair growth, but the intensity and duration of inflammation are crucial. Too much can cause ulcers and scarring. Lower beam energy and fewer treatments are recommended to avoid damage.
16 citations
,
April 1978 in “Genetics Research” Mice with the ab gene have abnormal sebaceous gland development, affecting sebum production.
14 citations
,
September 2018 in “Asian-Australasian Journal of Animal Sciences” Rex rabbits' hair follicles develop dynamically in the first 8 weeks, with key genes and proteins changing over time.
13 citations
,
May 2022 in “Cell discovery” The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
13 citations
,
January 2021 in “Scientific Reports” Pannexin 3 helps skin and hair growth by controlling a protein called Epiprofin.
12 citations
,
November 2020 in “Journal of Dermatological Science” Found microRNA differences in hair cells, suggesting potential treatment targets for hair loss.
10 citations
,
January 2016 in “PLOS ONE” Researchers found 44 proteins that change during different hair growth stages and may be important for hair follicle function.
8 citations
,
May 2021 in “Applied Materials Today” New nano composite helps reduce scars and regrow hair during burn wound healing.
7 citations
,
March 2021 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” Blocking prolactin increases the activity of secondary hair follicles in cashmere goats.
6 citations
,
June 2021 in “Developmental biology” Dermal EZH2 controls skin cell development and hair growth in mice.
5 citations
,
October 2014 in “Methods” The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.
5 citations
,
September 2012 in “Journal of Investigative Dermatology” Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.
2 citations
,
July 2021 in “Biochemical and Biophysical Research Communications” CTHRC1 helps hair grow back, and plantar dermis mixture boosts it.
1 citations
,
July 2013 in “Hair transplant forum international” Advancements in hair follicle culture have led to better understanding and potential treatments for hair loss.
1 citations
,
September 2009 in “Regenerative Medicine” Bioaesthetic therapies could improve healthcare if they safely regenerate cells, tissues, or organs to restore normal function.
January 2025 in “Institutional Repositories DataBase (IRDB)” Maslinic acid from olive extracts promotes hair growth like minoxidil.
New methods efficiently isolate dermal papilla cells from hair follicles, preserving their characteristics better than traditional methods.
January 2024 in “Journal of cellular immunology” Hair follicle stem cells are important for maintaining healthy skin and interact with many signals.