research Basic concepts, current evidence, and future potential for gene therapy in managing cutaneous wounds
Gene therapy shows promise for improving wound healing, but more research is needed for human use.
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research Concentrated Conditioned Medium-Loaded Silk Nanofiber Hydrogels with Sustained Release of Bioactive Factors To Improve Skin Regeneration
The hydrogel with bioactive factors improves skin healing and regeneration.
research The Thinning Top: Why Old People Have Less Hair
Old people have less hair because their hair follicles don't regenerate as well, not because of fewer stem cells, and a protein called follistatin might help reactivate hair growth.
research There and Back Again: Hair Follicle Stem Cell Dynamics
Hair follicle stem cells can return to their original niche and help regenerate hair.
research Can an in vitro hair drug model be developed using dermal papilla cells alone?
Dermal papilla microtissues could be useful for initial hair growth drug testing.
research Connexin 43 expression in the testes during postnatal development of finasteride-treated male rat offspring
Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.
research Author response: Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation
Fgf20 helps form hair follicle structures by stopping cell division and increasing cell movement.
research 1313 Fzd2 controls multiple aspects of epidermal development through distinct signaling mechanisms
Fzd2 is important for skin and hair development through various signaling ways.
research The amazing miniorgan: Hair follicle
Understanding hair follicles can lead to new treatments for hair loss and skin tumors.
research A novel cell-free regenerative therapy for hair loss: human fetal cartilage progenitor cell secretome
A new therapy using secretions from fetal cartilage cells shows promise for safe and effective hair regrowth.
research Enhancing hair regrowth using rapamycin-primed mesenchymal stem cell-derived exosomes
Rapamycin-primed exosomes can significantly boost hair regrowth.
research ARHGEF3 Regulates Hair Follicle Morphogenesis
ARHGEF3 is essential for proper hair follicle development.
research Epidermal retinol dehydrogenases cyclically regulate stem cell markers and clock genes and influence hair composition
Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.
research 910 Transepidermal UV radiation of human scalp skin induces distinctive hair follicle damage, which is mitigated by topical caffeine treatment
Caffeine can protect scalp hair follicles from damage caused by UV radiation.
research Stem Cells in the Body
Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.
research Hormonal Regulation and Systemic Signals of Skin Aging
Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.
research 281 Phase I/IIa clinical trial for the treatment of androgenetic alopecia using intradermal injections of cultured autologous dermal sheath cup cells
Injections of special skin cells showed potential in treating hair loss, with some participants experiencing increased hair density.
research Effects of RF Electric Currents on Hair Follicle Growth and Differentiation: A Possible Treatment for Alopecia
RF-based therapies might help treat hair loss.
research 190 Deficiency of the Human Cysteine Protease Inhibitor Cystatin M/E Causes Hypotrichosis and Dry Skin
Not having enough cystatin M/E protein causes less hair growth and dry skin.
research Effects of epidermal growth factor, fibroblast growth factor, minoxidil and hydrocortisone on growth kinetics in human hair bulb papilla cells and root sheath fibroblasts cultured in vitro
EGF and FGF boost hair cell growth, hydrocortisone slows it, and minoxidil doesn't affect it.
research Structure-guided PEGylated fibroblast growth factor 2 variants accelerate wound healing with improved stability
Compound 6 is a promising candidate for better wound healing.
research Aging, alopecia, and stem cells
The document concludes that both internal stem cell factors and external influences like the environment and hormones affect hair loss and aging, with potential treatments focusing on these areas.
research Histopathology of alopecia areata, acute and chronic: Why is it important to the clinician?
Recognizing the different stages of alopecia areata is crucial for accurate diagnosis and treatment.
research The Pathogenesis of Alopecia Areata in Rodent Models
Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.
research Efficacy of subcutaneous injection of platelet-rich plasma in alopecia: A clinical and histological pilot study on a rat model with a six-month long-term follow-up experience
Injecting platelet-rich plasma under the skin significantly improves hair growth and quality without harmful effects.
research Partial regrowth of scalp hair in a patient treated with extracorporeal pholtochemotherapy and interferon ? 2a
A patient with a severe type of hair loss experienced partial hair regrowth after treatment with a specific light therapy and a medication called interferon α2a.
research Immunologic findings in central centrifugal cicatricial alopecia
CCCA may be caused by both hair traction and an immune response.
research 1367 The protective role of miR-486 for alopecia areata
miR-486 may help prevent hair loss in alopecia areata.
research Topical botanical extract for management of chemotherapy-induced alopecia
A botanical extract may help manage hair loss from chemotherapy by preventing cell death in hair follicles.
research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne
Anti-acne medications may work by reducing the activity of a protein involved in acne development.