18 citations
,
January 2019 in “European journal of histochemistry” Cattle skin has leptin which might control skin and hair growth.
1 citations
,
May 2016 in “Journal of Cosmetic Dermatology” Cytokeratins 15 and 19 may help track vitiligo treatment progress.
6 citations
,
October 2022 in “Journal of cell science” Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.
12 citations
,
November 2014 in “PLOS Computational Biology” The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
8 citations
,
November 2020 in “Nature Communications” Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Linalool in personal care products may contribute to hair loss by damaging hair follicle stem cells and triggering harmful immune responses.
Linalool in personal care products may worsen frontal fibrosing alopecia by damaging hair follicle stem cells and triggering harmful immune responses.
43 citations
,
February 2008 in “Journal of cutaneous pathology” Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
27 citations
,
December 2005 in “Journal of Cutaneous Pathology” The malignant pilomatricoma showed strong epithelial keratin expression, suggesting it may not calcify.
3 citations
,
November 2022 in “Frontiers in Medicine” Onychopapilloma likely originates from the nail bed, not the nail matrix.
1 citations
,
July 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.
63 citations
,
July 2006 in “British Journal of Dermatology” Psoriasis causes changes in certain keratins and shrinks sebaceous glands in the scalp.
265 citations
,
March 1993 in “The EMBO Journal” Keratinocyte growth factor significantly alters skin and tissue development.
252 citations
,
March 1998 in “Developmental dynamics” FGFs-4, -8, and -9 have overlapping roles and are repeatedly used in tooth development.
248 citations
,
April 1988 in “Differentiation” Human and bovine hair follicles have distinct cytokeratins specific to hair-forming cells.
187 citations
,
May 1988 in “Differentiation” Trichocytic cytokeratins are found in hair, nails, tongue, and thymus cells, showing complex regulation in tissue development.
124 citations
,
December 1988 in “Differentiation” Trichocytic differentiation starts in cells with epithelial cytokeratins, transitioning to trichocytic cytokeratins in hair and gradually in nails.
72 citations
,
June 2001 in “Journal of Investigative Dermatology” S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.
69 citations
,
August 1999 in “Developmental biology” The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
44 citations
,
May 1997 in “Journal of Biological Chemistry” The human keratin 6a gene's specific sequences trigger expression in skin layers after injury.
29 citations
,
February 2010 in “British Journal of Dermatology” Snail1 may contribute to fibrosis in frontal fibrosing alopecia in postmenopausal women.
8 citations
,
July 2015 in “European journal of histochemistry” Sox9 is present in most canine skin tumors and may help understand stem cells' role in these cancers.
6 citations
,
July 2018 in “Steroids” Testosterone changes how certain channels work in male rat reproductive tracts, affecting fertility-related fluid balance.
83 citations
,
February 1991 in “Development” Fos protein is crucial for cell transition to cornification in keratinized tissues.
2 citations
,
July 2024 in “Bioengineering” PRF lysates reduce inflammation in cancer cells and boost immune response in healthy oral cells.
Diseased horse foot skin shows increased keratin expression, similar to wound healing in mammals.
318 citations
,
October 1998 in “The Journal of Cell Biology” Keratin 17 is important for skin development and may help define skin cell types.
198 citations
,
March 1999 in “Journal of Investigative Dermatology” Keratin 15 helps maintain tissue integrity and is reduced in activated keratinocytes.
25 citations
,
January 2003 in “Plastic & Reconstructive Surgery” Nail-matrical fibroblasts can make non-nail cells produce hard keratin, useful for nail repair.
12 citations
,
June 2013 in “International Journal of Dermatology” Seborrheic keratosis shows varied cell differentiation, and keratin analysis helps diagnose skin tumors.