214 citations
,
April 2017 in “Cell” Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
57 citations
,
May 2007 in “Nature” Adult mice can grow new hair from skin wounds.
9 citations
,
March 2019 in “Science” Blocking cell death in certain stem cells can improve wound healing and tissue regeneration.
2 citations
,
September 2019 in “Romanian Journal of Pediatrics” Fetal skin can heal without scarring, offering insights for new scar-reducing treatments.
2 citations
,
November 2015 in “Actas Dermo-Sifiliográficas” Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.
May 2023 in “Journal of Endocrinology and Reproduction” Blocking cholesterol production may help control hair loss in Primary Cicatricial Alopecia by affecting key regulators.
85 citations
,
October 2015 in “Proceedings of the National Academy of Sciences of the United States of America” NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.
33 citations
,
March 2015 in “Experimental Dermatology” LHX2 and SOX9 identify unique hair follicle cell groups, crucial for hair maintenance.
28 citations
,
September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
6 citations
,
January 2009 in “Elsevier eBooks” The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.
The Wnt signaling pathway is essential for skin repair and healing.
47 citations
,
September 2015 in “Cell Cycle” Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.
3 citations
,
December 2020 The interdigital gland in crossbred sheep is similar to skin and has specialized structures for secretion.
April 2019 in “Journal of Investigative Dermatology” Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.
1 citations
,
January 2024 in “International journal of molecular sciences” TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.
21 citations
,
March 2019 in “Experimental Dermatology” Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.
February 1956 in “Bulletin of Experimental Biology and Medicine” Glycogen levels in mouse skin drop after injury but increase during healing, returning to normal within a month.
22 citations
,
August 2020 in “Cells” TGM3 is important for skin and hair structure and may help diagnose cancer.
38 citations
,
November 2020 in “International journal of biochemistry & cell biology” Keratin proteins are essential for keeping the cells in the human colon healthy and stable.
9 citations
,
November 2021 in “Frontiers in Cell and Developmental Biology” PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.
IL-1 signaling is crucial for hair follicle stem cell growth and wound healing.
19 citations
,
January 2013 in “Frontiers in Neuroanatomy” Zebrafish can help study and develop treatments for hearing loss.
September 2025 in “Digital Commons - RU (Rockefeller University)” Nfib in hair follicle stem cells boosts melanocyte stem cell growth and differentiation.
15 citations
,
September 2018 in “Applied Biological Chemistry” Matrigel supports cell growth and repair, and thymosin beta 4 aids tissue regeneration and healing.
3 citations
,
April 2022 in “F1000Research” Understanding biological mediators in skin healing can improve treatments for skin wounds.
44 citations
,
July 2020 in “Stem Cell Research & Therapy” Epidermal stem cells show promise for skin repair and regeneration.
22 citations
,
March 2021 in “Materials Today Bio” Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.
8 citations
,
August 2025 in “Journal of Translational Medicine” CD44 signaling can help heal wounds without scars.
7 citations
,
June 2020 in “npj regenerative medicine” GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
57 citations
,
December 2021 in “Nature Communications” Non-canonical Wnt signaling helps intestinal stem cells move to injury sites for tissue repair.