22 citations
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June 2013 in “International journal of molecular sciences” Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
18 citations
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November 2013 in “Molecules and Cells” New culture method keeps human skin stem cells more stem-like.
16 citations
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March 2019 in “Experimental dermatology” Injury changes how hair follicle stem cells behave, depending on the hair growth stage.
9 citations
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March 2013 in “Expert opinion on biological therapy” Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
7 citations
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August 2022 in “Nature communications” A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.
2 citations
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May 2019 in “Advances in wound care” Blood-derived CD34+ cells speed up healing, reduce scarring, and regrow hair in skin wounds.
2 citations
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January 2017 in “AIMS cell and tissue engineering” Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.
January 2026 in “MEDS Clinical Medicine” Biophysical and metabolic factors in skin wounds are crucial for stem cell behavior and skin healing.
January 2019 in “Advances in stem cells and their niches” Krox20 is important for cell differentiation in the brain and hair follicles.
33 citations
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December 2004 in “Differentiation” Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.
21 citations
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January 2024 in “Science Immunology” Regulatory T cells protect hair follicle stem cells by maintaining immune privilege in the skin.
11 citations
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June 2012 in “Journal of Dermatological Science” Scientists identified a group of human skin cells with high growth and regeneration potential.
10 citations
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March 2016 in “Development Growth & Differentiation” Scientists created feather buds in lab-grown chick skin using specific cell interactions.
March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Scientists can now create skin with hair by reprogramming cells in wounds.
184 citations
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November 2014 in “Developmental Cell” Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.
71 citations
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October 2017 in “Journal of Investigative Dermatology” PPAR-γ agonists like pioglitazone may help manage lichen planopilaris but don't fully reverse scarring.
62 citations
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April 2009 in “British Journal of Dermatology” Epidermal stem cells could lead to new treatments for skin and hair disorders.
56 citations
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March 2015 in “Cell death and differentiation” Older skin has higher cancer risk due to inflammation and stem cell issues.
49 citations
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March 2014 in “Journal of Investigative Dermatology” Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.
43 citations
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December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
33 citations
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March 2015 in “Experimental Dermatology” LHX2 and SOX9 identify unique hair follicle cell groups, crucial for hair maintenance.
12 citations
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September 2020 in “Stem cell research & therapy” Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
5 citations
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September 2010 in “Cancer Prevention Research” The research suggests new treatments for skin cancer could target specific cell growth pathways.
3 citations
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November 2020 in “PubMed” Stiffer hydrogels better promote stem cells turning into hair follicle cells.
1 citations
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June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.
36 citations
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February 2006 in “Biochemical and Biophysical Research Communications” Wnt-10b helps skin cells develop into hair-related structures.
211 citations
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May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
26 citations
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July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
293 citations
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November 2011 in “Nature” The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.
105 citations
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October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.