38 citations
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June 2017 in “The Journal of Dermatology” Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
19 citations
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July 2011 in “Microscopy and Microanalysis” The hair follicle bulge is an important area for adult stem cells involved in hair growth and repair, with potential for medical use needing more research.
4 citations
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May 2014 in “Biochemical Society Transactions” Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.
2 citations
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May 2022 in “Stem cell research & therapy” Disrupted stem cell signals in hairpoor mice cause hair loss.
November 2025 in “Journal of Investigative Dermatology” Alopecia Areata may involve reduced antioxidant defenses in hair follicles, affecting stem cell function.
2 citations
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June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Corneal regeneration relies on distinct stem cell compartments in the limbal niche.
305 citations
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June 2012 in “Nature” Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.
21 citations
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January 2024 in “Science Immunology” Regulatory T cells protect hair follicle stem cells by maintaining immune privilege in the skin.
14 citations
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April 2016 in “Cell Transplantation” Neural stem cell extract can safely promote hair growth in mice.
10 citations
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July 2019 in “Advances in Wound Care” Reducing Flightless I protein improves wound healing by activating skin stem cells.
42 citations
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March 2008 in “Molecular and Cellular Endocrinology” Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
11 citations
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September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific group of skin stem cells was found to help maintain hair follicle cells.
September 2025 in “Journal of Investigative Dermatology” SLC3A2 is crucial for hair follicle stem cell function and hair growth.
August 2025 in “Journal of Investigative Dermatology” Fibronectin is essential for hair follicle regeneration and may help rejuvenate aged skin.
33 citations
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March 2015 in “Experimental Dermatology” LHX2 and SOX9 identify unique hair follicle cell groups, crucial for hair maintenance.
6 citations
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September 2017 in “Experimental and Therapeutic Medicine” Shortened PEDF peptides speed up skin wound healing by boosting cell growth.
61 citations
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July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
15 citations
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November 2020 in “Development” Stem cells in the eye have different roles and behaviors, helping maintain and repair the eye's surface.
13 citations
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September 2019 in “EBioMedicine” sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.
294 citations
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February 2011 in “Cell” Nephronectin helps attach muscle cells to hair follicles.
74 citations
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October 2023 in “Nature Reviews Molecular Cell Biology” 27 citations
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February 2020 in “EMBO Reports” MEX3A is crucial for maintaining intestinal stem cells in mice.
321 citations
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January 2012 in “Cell stem cell” TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
25 citations
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December 1992 in “Seminars in cell biology” Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
4 citations
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October 2018 in “Cell Stem Cell” Hox genes control hair growth patterns in mammals by regulating stem cell activity in the skin.
April 2021 in “Journal of Investigative Dermatology” Krox20 is crucial for hair growth and maintaining skin stem cells.
387 citations
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November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
283 citations
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February 2011 in “Cell stem cell” COL17A1 is crucial for preventing hair graying and loss by supporting hair and pigment stem cells.
260 citations
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June 2011 in “Cell” Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.