research Genotoxic Agents: An Unexpected Effect on Healthy Epithelia
Chemotherapy drugs can cause abnormal growth and changes in healthy skin and gland cells.
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research Fibroblast Growth Factors in Epithelial Homeostasis and Repair
Fibroblast Growth Factors (FGFs) help maintain and repair skin tissues, which is important for preventing diseases like inflammation, fibrosis, and cancer.
research Regular expression of hair follicle keratins as crucial factors in tissue engineering of hair follicles
Keratins are key to developing and regenerating hair follicles for treating hair loss.
research Scaffold-based developmental tissue engineering strategies for ectodermal organ regeneration
Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.
research Bioactive Glasses: Advancing Skin Tissue Repair through Multifunctional Mechanisms and Innovations
Bioactive glasses help heal skin wounds by promoting tissue repair and preventing infections.
research Cell/Tissue Microenvironment Engineering and Monitoring in Tissue Engineering, Regenerative Medicine, and In Vitro Tissue Models
Engineering the cell microenvironment is key for advancing tissue engineering and regenerative medicine.
research Three-dimensional ultrastructural analysis of human skin with the arrector pili muscle interacting with the hair follicle epithelium
The method effectively analyzes skin tissue changes, especially in the arrector pili muscle and nerve fibers with hair follicles.
research Novel tissue mechanics-guided cellular flows drive the formation of feather follicles
Feather follicles form through specific cellular flows and mechanical changes in the skin.
research Novel Tissue Mechanics-Guided Cellular Flows Enable the Evolution of Feather Follicles
Cellular flows and tissue mechanics guide feather follicle formation in birds.
research ROLE OF FERROPORTIN-MEDIATED IRON RELEASE FROM MACROPHAGES IN TISSUE HOMEOSTASIS AND REPAIR
Ferroportin in macrophages is crucial for hair growth and skin healing by managing iron distribution.
research Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation
The Kras mutation changes normal cell signals, leading to disrupted tissue structure and potential cancer.
research LB1011 Oncogenic ras mutation induces spatiotemporally specific tissue deformation through converting fluctuated into sustained ERK activation
A specific mutation in Kras causes abnormal tissue changes by making a cell signal continuously active, which disrupts normal cell coordination.
research Streamlined intravital imaging approach for long-term monitoring of epithelial cell dynamics on an inverted confocal microscope
A new tool allows easier long-term imaging of live skin cells, helping study diseases like skin cancer.
research [Skin tissue engineering in China].
China made major progress in creating artificial skin for better burn treatment.
research 1469 Tissue mechanics partake in spatiotemporal patterning of wound-induced hair neogenesis in African spiny mouse
African spiny mice can regenerate skin and hair after wounds due to specific tissue mechanics.
research Dedifferentiation of committed epithelial cells into stem cells in vivo
Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.
research Transcriptional profiling of putative human epithelial stem cells
Alpha 6 + /MHCI - cells have stem cell traits and are similar to mouse hair follicle stem cells.
research Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence
Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
research Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture
Mechanical forces are crucial for shaping cells and forming tissues during development.
research Epithelial Fibronectin meshwork controls skin regeneration
Fibronectin is essential for hair follicle regeneration by supporting stem cells.
research Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle
Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
research Quiescent Tissue Stem Cells Evade Immune Surveillance
Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
research Ex Vivo Organ Culture of Human Hair Follicles: A Model Epithelial–Neuroectodermal–Mesenchymal Interaction System
Hair follicle culture helps study cell interactions and effects of substances on tissue growth.
research Tissue Resident Foxp3+ Regulatory T Cells: Sentinels and Saboteurs in Health and Disease
Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.
research Scaffolds for epithelial and hair follicle regeneration
Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
research Vascular endothelial cells as signaling niches for epithelial stem cells in the skin
Vascular endothelial cells may significantly influence skin stem cells, but more research is needed.
research Exosomes serve as a crucial mediator of epithelial–fibroblast communication during hair follicle morphogenesis in cashmere goats
Exosomes help hair follicle development in cashmere goats.
research Engineered building bloks to print endogenous tissue and complex organs in vitro
New bio-ink can print complex tissues and organs.
research Cutaneous Epithelial Stem Cells
Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
research Epithelial‐to‐mesenchymal transition in cutaneous wound healing: Where we are and where we are heading
The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.