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Finding functions for unknown GPCRs is hard but key for making new drugs.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.

EDA is vital for bone and cartilage formation and could help treat skeletal disorders.

Higher GPER-1 levels are linked to more severe and shorter-duration androgenetic alopecia, suggesting GPER-1 as a potential treatment target.

Both estrogens and androgens are important for health in both males and females.

PRP is effective for treating hair loss, especially with other treatments.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Plant-based products can improve hair and skin health without harmful side effects.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Testosterone affects vascular cells directly without converting to estradiol.

Targeting androgen receptors shows promise for treating triple-negative breast cancer, but more research is needed.

δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.

Men with androgenetic alopecia have oilier and less hydrated scalps, especially in sensitive areas.

Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.

Lipedema is a painful fat disorder in women that's hard to treat, often worsens with hormonal changes, and requires symptom-focused therapies.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might decrease the risk. AST also lessens the chance of cancer coming back but doesn't really affect survival rates. More research is needed to understand AST's benefits for different bladder cancers.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

Drugs can change hair growth and this is important because it can upset people.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

Scopolin and scopoletin from Merremia peltata leaves may help treat hair loss and showed promising results in rabbit tests.

Cannabidiol shows promise as an effective treatment for acne.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.