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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Artemis phosphorylation at Ser516 may help regulate skin and hair structures.

Human keratinocytes do not naturally respond to androgens.

The type of tumor suppressor affects the form of skin cancer from hair follicle stem cells.

Seven new genetic risk areas for prostate cancer were found.

The 4C32 gene may help in mouse skin development and differentiation.

A specific gene mutation causes long hair in Angora rabbits.

Overexpressing the glucocorticoid receptor in mice leads to abnormal skin development and reduced inflammation.

Radiation therapy in breast cancer patients changes gene expression related to DNA damage, fibroblast growth, and hair follicle development, which could help improve treatment for radiation-induced fibrosis.

CRISPR-Cas9 successfully edited genes in Cashmere goats, affecting hair growth.

Tissue environment greatly affects the unique epigenetic makeup of regulatory T cells, which could impact autoimmune disease treatment.

Colorectal cancer cells can adapt without losing their traits or drug sensitivity.

CK 19 expression is higher in more severe skin cancers.

RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.

Super-enhancers control CD25 expression in specific cell types, affecting immune function.

EGFR-targeted cancer therapy can cause skin issues starting at hair follicles, leading to inflammation.

Neuregulin3 affects cell development in the skin and mammary glands.

Researchers found a new mutation causing total hair loss from birth.

Combining irinotecan and cetuximab is effective for some metastatic colorectal cancer patients but often causes manageable skin issues.

Human epidermal neural crest stem cells could be used for therapies, drug discovery, and disease modeling.

Increasing PDCD4 protein may help prevent or treat some skin cancers.

Genetic variants in specific genes cause central centrifugal cicatricial alopecia.

The research suggests that autophagy-related genes might play a role in causing alopecia areata.

Regular endoscopic checks are crucial for Cronkhite-Canada syndrome patients to catch potential cancers early.

Reconstructed skin models are useful for studying how skin processes certain chemicals.

Overexpression of Hoxc13 in hair cells causes hair loss and skin issues.

The L412F variant of TLR3 is linked to skin infections, more viral infections, and autoimmune issues.

Targeted cancer therapies can cause skin side effects, but activating SOS in the skin may help reduce them.

Research from 2011 to 2020 shows androgen receptors could be key for prognosis and treatment in certain breast cancers.

Diagnosing and managing Glucocorticoid Resistance Syndrome is complex due to genetic differences and varied symptoms.