3 citations
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October 2015 in “PubMed” Most men stopped using the hair loss treatment not because of sexual side effects, but because they didn't see positive results.
August 2021 in “The Journal of Urology” Finasteride use is strongly linked to sexual dysfunction, especially in young men treating hair loss.
31 citations
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January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
June 2017 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride's sexual side effects not caused by androgen deficiency or SRD5A inhibition.
May 2022 in “The Journal of Sexual Medicine” Amoxapine may be effective for treating ejaculatory dysfunction.
January 2016 in “The Korean Journal of Internal Medicine” Doxazosin may cause breast enlargement and pain in men.
December 2023 in “Revista Urología Colombiana / Colombian Urology Journal” More research is needed to find effective treatments for sickle cell disease-related priapism.
September 2018 in “Translational Andrology and Urology”
1054 citations
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February 1998 in “The New England Journal of Medicine” Finasteride reduces urinary issues and surgery need in men with enlarged prostates by over 50%.
April 2017 in “The journal of sexual medicine” 5-alpha-reductase inhibitors significantly affect the penile tissue of hypertensive rats.
August 2018 in “Daehan binyogi jong-yang haksulji” Taking sildenafil and finasteride together is safe and improves urinary and sexual symptoms in BPH patients.
15 citations
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January 2017 in “Advances in Experimental Medicine and Biology” 5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.
May 2022 in “The Journal of Sexual Medicine” Finasteride is linked to sexual dysfunction, especially in younger men using it for hair loss.
1 citations
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February 2008 in “Nature Clinical Practice Urology” Finasteride's sexual side effects may be due to nocebo effect.
1 citations
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September 2016 in “Actas Dermo-Sifiliográficas” 5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.
20 citations
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June 2017 in “Hormone Molecular Biology and Clinical Investigation” Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.
November 2024 in “Journal of Family Medicine and Primary Care” 5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.
October 2020 in “Reactions Weekly” Finasteride can cause multiple side effects like tremors, dry skin, and rapid aging.
October 2017 in “The Journal of Urology” Finasteride reduces the need for prostate surgery but may increase the risk of depression and persistent sexual side effects.
2 citations
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April 2019 in “Journal of Internal Medicine” Men using steroids or finasteride to look more attractive may harm their fertility and sexual function, creating a paradox where they seem fit but may be less able to reproduce.
April 2016 in “Journal of The American Academy of Dermatology” Finasteride and SSRIs together increase impotence and low libido risk in men.
1 citations
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July 2023 in “F&S Reviews” Some common medications may harm male fertility by affecting hormones, sperm production, and sexual function.
July 2025 in “Reactions Weekly” 1 citations
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June 2014 in “L Endocrinologo” Finasteride can cause lasting sexual and mood issues even after stopping the drug.
50 citations
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September 2016 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.
38 citations
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October 2014 in “Current Opinion in Endocrinology, Diabetes and Obesity” 5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.
These medications for BPH have known risks and may have new side effects.
The paper suggests that a decrease in estrogen receptor activity may cause sexual dysfunction syndromes and proposes hormonal treatments.
February 2024 in “The journal of sexual medicine” Flibanserin shows promise for treating male sexual dysfunction but has side effects like insomnia and fatigue.
27 citations
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April 2011 in “Folia Histochemica et Cytobiologica” DHT deficiency can disrupt cell connections in rat testes, possibly affecting fertility.