research Serum markers thrombophilia in pregnant women with Systemic Lupus Erythematosus
Pregnant women with Systemic Lupus Erythematosus have a higher risk of blood clotting problems.
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810-840 / 1000+ results research The Clinical Features and Outcomes of Systemic Lupus Erythematosus in Ageing Patients
SLE in ageing patients is less severe and needs careful treatment to avoid excess.
research A case of systemic lupus erythematosus complicated with aortic regurgitation due to bacterial endocarditis
Dental procedures and immunosuppressants can lead to heart infections in lupus patients.
research Soft-tissue calcification in systemic lupus erythematosus
Soft-tissue calcification is rare in systemic lupus erythematosus.
research Multibacillary leprosy with positive serology misdiagnosed as systemic lupus erythematosus
A woman was wrongly diagnosed with lupus but actually had leprosy.
research Favourable interactions of cytostatic and steroid drugs in treatment of systemic lupus erythematosus.
Combining cytostatic and steroid drugs effectively treats systemic lupus erythematosus.
research Acute pancreatitis: An unusual presentation of systemic lupus erythematosus
Early diagnosis and aggressive treatment are crucial for managing SLE-related pancreatitis in children.
research Dermoscopic characterization and clinical application of four facial erythematous inflammatory dermatoses
The document concludes that specific dermoscopic features can help diagnose different facial red skin conditions.
research Long non-coding RNA Xist contribution in systemic lupus erythematosus and rheumatoid arthritis
Females are more prone to lupus and arthritis due to X chromosome factors.
research Immunohistologic findings in the lung in systemic lupus erythematosus.
SLE affects lungs and kidneys similarly due to immune complexes.
research New developments in the treatment of systemic lupus erythematosus
New treatments for lupus show promise, but more research is needed, especially for children.
research A Case Report of Thrombotic Thrombocytopenic Purpura Associated with Systemic Lupus Erythematosus: Overlapping Features
Early diagnosis, intensive therapy, and careful follow-up are crucial for managing overlapping TTP and SLE.
research The effect of DNMTs and MBPs on hypomethylation in systemic lupus erythematosus
Certain proteins involved in DNA modification may affect the genetic changes in systemic lupus erythematosus and could indicate the disease's activity.
research Castleman’s Disease Combined with the Development of Systemic Lupus Erythematosus
A 16-year-old boy with Castleman's disease and lupus was successfully treated and showed no recurrence.
research Efficacy Observation on Mild to Moderate Active Systemic Lupus Erythematosus Treated with Compound Zishenqing Formula
The compound zishenqing formula is effective and safe for treating mild to moderate systemic lupus erythematosus.
research Muscle weakness of the lower limbs after epidural anesthesia in a pregnant woman with undiscovered systemic lupus erythematosus
Undiagnosed lupus can cause severe complications after epidural anesthesia, leading to muscle weakness and potentially death.
research Case Report: Rare aplastic anemia in pediatric systemic lupus erythematosus: a case series and systematic literature review
Early detection and infection prevention are crucial for improving survival in pediatric lupus patients with aplastic anemia.
research First‐degree relatives of patients with systemic lupus erythematosus: Autoreactivity but not autoimmunity?
Relatives of lupus patients show signs of immune system activity but not full-blown lupus.
research Inaugural complete heart block in anti-SSA negative systemic lupus erythematosus: the diagnostic role of anti-PM-Scl 100 antibodies
Complete heart block in lupus may be linked to microvascular issues and anti-PM-Scl 100 antibodies, not just traditional markers.
research Divergence between initial and cumulative manifestations in systemic lupus erythematosus: effect of age and sex in a prospective lupus cohort from Pakistan
This prospective cohort study of 185 SLE patients in Pakistan, with 138 complete datasets, highlights that arthritis and mucocutaneous features, such as hair loss, are prevalent at disease onset, while sicca, vasculitis, and hematologic manifestations increase over time. The study found significant cumulative increases in mucocutaneous involvement, sicca features, hematologic manifestations, vasculitis, and nephritis. Pediatric patients showed higher rates of mucocutaneous features, and males had higher nephritis rates at onset. These findings emphasize the need for age- and sex-specific monitoring in SLE management.
research Hair loss and bronze discoloration of the skin in lupus erythematosus
research Calcinosis Cutis in a Patient With Systemic Lupus Erythematosus: A Case Report
Early diagnosis and treatment of calcinosis cutis in lupus patients is crucial due to its rarity and potential complications.
research P44 An acutely unwell and rare presentation of systemic lupus erythematosus; a case report
Early recognition and treatment of SLE can improve outcomes in patients with complex symptoms.
research Acute parenchymal lung involvement in a 68-year-old woman with systemic lupus erythematosus, anemia, and thrombocytopenia
A 68-year-old woman with lupus and blood disorders improved after increased steroids and immunoglobulin treatment.
research Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus
The new SLICC criteria for diagnosing lupus are more sensitive and accurate than the old criteria.
research Mesenchymal stem cells and their secretome - candidates for safe and effective therapy for systemic lupus erythematosus
Mesenchymal stem cells and their secretome may offer a safe and effective treatment for systemic lupus erythematosus.
research Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus
The new criteria for classifying lupus are more accurate and comprehensive.
research Derivation and Validation of Systemic Lupus International Collaborating Clinics Classification Criteria for Systemic Lupus Erythematosus
The updated criteria improve the accuracy of diagnosing lupus.
research Cross-species comparative spatial transcriptomics of hair follicle-T cell interactions identifies conserved drivers of cutaneous lupus erythematosus skin disease and associated hair loss
This study investigates the interactions between T cells and hair follicles in cutaneous lupus erythematosus (CLE) across mice, dogs, and humans, focusing on the role of these interactions in skin disease and hair loss. The research identifies a 35% overlap in gene expression when autoreactive T cells are transferred in mice, with CD8 T cells contributing to extracellular matrix reorganization. Key findings include the identification of CXCR3 ligands and IFN response genes in hair follicles, conserved across species, and the alleviation of skin disease in mice through CXCR3 knockout on T cells. B cell depletion also reduces skin disease, aligning with human lupus therapies. The study highlights CFD and S100A8/9 as potential targets for future trials, emphasizing the role of CXCR3+ T cells and B cells in CLE lesional skin and their contribution to hair loss and inflammation.
research P47 Condition overlay and diagnostic delay – A challenging case of fibromyalgia and systemic lupus erythematosus
Timely diagnosis of SLE is crucial due to symptom overlap with fibromyalgia.