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April 2006 in “Experimental Neurology” Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.
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April 2024 in “Skin research and technology” Topical rosuvastatin and melatonin creams significantly reduce psoriasis severity and are safe.
April 2015 in “The FASEB Journal” Midazolam's antiseizure effects are mainly due to synaptic GABA-A receptors, not neurosteroids or extrasynaptic receptors.
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January 2019 in “Brazilian Journal of Pharmaceutical Sciences” Maidenhair fern extract reduced anxiety and depression in rats and may work due to its antioxidant and anti-inflammatory properties.
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December 2007 in “American Journal of Psychiatry” Finasteride may effectively reduce Tourette's syndrome symptoms and improve life quality.
July 2006 in “Inpharma Weekly” February 2026 in “Toxicology Letters” MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.
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November 2014 in “Clinical Therapeutics” Finasteride and tamsulosin hydrochloride can be safely taken together without significant interaction.
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August 2002 in “Journal of Medicinal Chemistry” New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
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September 2003 in “Journal of Medicinal Chemistry” A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.
June 2024 in “Drug and therapeutics bulletin” Finasteride can cause depression, suicidal thoughts, and lasting psychiatric and sexual issues.
January 2026 in “Pharmaceutical journal/The pharmaceutical journal” Finasteride and dutasteride now have stronger warnings for psychiatric and sexual side effects.
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January 1984 in “Progress in neuro-psychopharmacology & biological psychiatry” Benzodiazepines changed hormone levels but did not affect hair growth in women with idiopathic hirsutism.
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June 2013 in “Journal of Neuroendocrinology” Neurosteroids may help prevent seizures and slow epilepsy progression.
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August 2023 in “Saudi Pharmaceutical Journal” Niosomes can effectively deliver cetirizine topically for treating alopecia.
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June 1975 in “Journal of Steroid Biochemistry” Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.
August 2023 in “Revista Ibero-Americana de Humanidades, Ciências e Educação” People with skin conditions like psoriasis and eczema have higher anxiety levels.
February 2025 in “Ciencia Latina Revista Científica Multidisciplinar” Finasteride can help with hair loss and prostate issues but may negatively affect mood and the nervous system.
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September 1981 in “PubMed” Cyproterone acetate effectively treats virilized women, especially under 35, despite some side effects.
November 2014 in “Clinical Neurophysiology” High doses of progesterone can reduce seizures in mice.
June 2021 in “Reactions Weekly” Finasteride caused serious side effects and led to six suicides.
August 2018 in “Journal of The American Academy of Dermatology” Finasteride, a hair loss drug, is linked to increased suicidal thoughts, particularly when used for hair loss.
January 2014 in “eScholarship (California Digital Library)” Targeting specific GABA receptors may help treat epilepsy and postpartum depression.
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July 2009 in “Experimental and clinical endocrinology & diabetes” Cyproterone acetate effectively treats sexual disorders by reducing sexual functions and is generally well-tolerated.
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February 2019 in “Journal of clinical medicine” Atorvastatin reversed memory problems caused by cancer drug trastuzumab and improved its cancer-fighting abilities without causing hair loss.
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January 2013 in “UNICA IRIS Institutional Research Information System (University of Cagliari)” Hormonal contraceptives may reduce social behavior and sexual motivation by lowering allopregnanolone levels.
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February 1999 in “PubMed” Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.