research Enhanced delivery of drugs into and across the skin by ethosomal carriers
Ethosomal carriers improve drug delivery through the skin better than traditional methods.
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research Testosterone implants in women: Pharmacological dosing for a physiologic effect
Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.
research Progesterone in gender-affirming therapy of trans women
Progesterone may help trans women with breast development and health, but more research is needed.
research Antiandrogenic progestins for treatment of signs of androgenisation and hormonal contraception
Certain hormone medications can treat symptoms like acne and unwanted hair, regulate periods, and prevent pregnancy in women and teenage girls.
research Localized corticosteroid delivery in alopecia areata using microneedle patch technology
research Development of Cosmeceutical Based Drug Delivering Micro Patch System
A microneedle patch system was developed for quick, convenient, and efficient delivery of hair loss treatment drug, Finasteride.
research Ion pairs of risedronate for transdermal delivery and enhanced permeation rate on hairless mouse skin
Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.
research Dissolving microneedle patch loading dutasteride microspheres for the long-acting treatment of androgenetic alopecia
A dissolving microneedle patch with dutasteride offers effective, long-lasting hair loss treatment with fewer side effects.
research Postmenopausal hormone replacement therapy and changes in skin connective tissue
Hormone replacement therapy improves skin health and reduces aging signs in postmenopausal women.
research The injectable contraceptives depot medroxyprogesterone acetate and norethisterone enanthate substantially and differentially decrease testosterone and sex hormone binding globulin levels: A secondary study from the WHICH randomized clinical trial
Both injectable contraceptives lower testosterone and SHBG levels, with NET-EN having a greater effect than DMPA-IM.
research Enhanced ex vivo skin retention of bicalutamide using a nano-in-micro composite: Drug-loaded lipid vesicles in a dissolving microarray patch
The new drug delivery system improves bicalutamide skin retention for better treatment of hair loss.
research 1386 Estetrol prolongs anagen in healthy female scalp hair follicles by positively modulating dermal papilla functions and generation of progenitor stem cells ex vivo
Estetrol may help prevent hair loss and promote hair growth in women.
research Dienogest
Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.
research Transethosomes: A Breakthrough System for Transdermal and Topical Drug Delivery
Transethosomes improve drug delivery through the skin by overcoming the outer skin layer's barrier.
research FRI378 Estetrol Prolongs Anagen In Healthy Female Scalp Hair Follicles By Positively Modulating Dermal Papilla Functions And Generation Of Progenitor Stem Cells Ex Vivo
Estetrol helps keep scalp hair in the growth phase longer and improves hair follicle health by affecting the hair root and increasing stem cells.
research Polymer conjugated retinoids for controlled transdermal delivery
A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with less inflammation.
research Effects of depot medroxyprogesterone acetate, the copper IUD and the levonorgestrel implant on testosterone, sex hormone binding globulin and free testosterone levels: ancillary study of the ECHO randomized clinical trial
The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.
research Sex Hormones and Related Compounds, Including Hormonal Contraceptives
Hormonal contraceptives and related compounds can increase health risks like thrombosis and affect sexual function.
research Progestogens with Antiandrogenic Properties
research LB1047 Comparative analysis of cutaneous hormonal profiles in pre-menopausal and post-menopausal women
Skin hormone levels change significantly after menopause.
research New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors.
Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.
research Transdermal film-loaded finasteride microplates to enhance drug skin permeation: Two-step optimization study
Optimized film improves finasteride skin absorption and treatment efficiency.
research News & Notes
Loop diuretics may double bone loss in elderly men, finasteride lowers prostate cancer risk but may increase high-grade tumors, abarelix reduces testosterone quickly, and transdermal testosterone offers minimal sexual benefit for women.
research Estranys matins de febrer: Pauline Fondevila
Trienones are more effective at inhibiting the enzyme linked to hair loss than dienones.
research Percutaneous absorption of a new antiandrogen included in liposomes or in solution
Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.
research IMPROVED SKIN PENETRATION AND DEPOSITION OF NAFTIFINE FROM TRANSETHOSOMES AND TRANSETHOSOMAL GEL FORMULATIONS
Transethosomal gels improve naftifine skin delivery better than Exoderil cream.
research Transdermal finasteride delivery via powder-carrying microneedles with a diffusion enhancer to treat androgenetic alopecia
Microneedles with enhancer effectively promote hair growth and increase hair density.
research Normalization of testosterone levels using a low estrogen-containing oral contraceptive in women with polycystic ovary syndrome.
Loestrin effectively normalizes testosterone levels and improves PCOS symptoms with minimal side effects.
research Regulation of epidermal proliferation and hair follicle cycling by synthetic photostable retinoid EC23
The synthetic retinoid EC23 thickens skin and promotes hair growth more effectively and with a lower dose than natural retinoids.
research Bifunctional sodium hyaluronate microneedle patches integrating 5α-reductase and ROS regulation for boosted hair regeneration
The microneedle patch boosts hair growth by reducing DHT and oxidative stress.