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Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.

Progesterone and testosterone protect brain cells from damage through specific pathways.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Both cyproterone acetate and spironolactone effectively reduce hair growth in women with hirsutism.

Transgender females can reach their target estrogen levels using estradiol patches, especially if oral treatments fail or if they're at risk for blood clots. Often, the highest dose patch is needed.

Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.

Epristeride's metabolism involves key metabolites and proteins, affecting its use in doping tests.

COCs often cause nausea, vomiting, and hair loss, while Depo-Provera is linked to weight gain.

Prostate cells have proteins that bind to specific hormones, which can increase protein production when activated by these hormones.

Leuprolide may better manage cholesterol and blood pressure in PCOS than spironolactone.