9 citations
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August 2021 in “Biomedicines” 17β-estradiol boosts APE1/Ref-1 secretion in cells and mice via a calcium-dependent pathway.
9 citations
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March 1985 in “Head & Neck Surgery” Topical minoxidil is the most promising treatment for male pattern hair loss, but more research is needed to confirm its effectiveness and safety.
4 citations
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August 2019 in “General and Comparative Endocrinology” Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.
2 citations
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November 2011 in “InTech eBooks” Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.
Certain genes may influence hair loss differently in men and women.
October 2015 in “药物不良反应杂志” Stopping the drug usually helps, but tamoxifen or surgery may be needed if symptoms persist.
December 2016 in “The Journal of urology/The journal of urology” Castration significantly reduces prostate size and BPH symptoms.
51 citations
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March 2018 in “Journal of Investigative Dermatology” Current murine models need improvement for better human wound healing research translation.
26 citations
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January 1982 in “Hormone Research” Normal androgen levels need ACTH, and different mechanisms control adrenarche and gonadarche.
20 citations
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May 1998 in “PEDIATRICS” African-American girls tend to start puberty earlier than white girls, possibly due to increased androgen production.
88 citations
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September 2003 in “Clinical endocrinology” Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.
37 citations
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September 2003 in “Journal of Medicinal Chemistry” A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.
30 citations
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December 1999 in “Journal of Investigative Dermatology Symposium Proceedings” Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.
14 citations
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June 2015 in “Toxicology and Industrial Health” Low doses of BPA can increase prostate growth and change hormone levels in adult rats.
515 citations
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April 2003 in “Endocrine Reviews” Androgens and DHEA can help prevent breast cancer and improve health in women.
19 citations
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May 2013 in “Annals of Oncology” Aromatase inhibitors cause male pattern hair loss in women.
658 citations
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June 2003 in “Endocrine reviews” Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
60 citations
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June 1997 in “Baillière's clinical obstetrics and gynaecology” PCOS is often caused by hormonal imbalances that can lead to various health issues and may indicate a risk for future metabolic and cardiovascular problems.
40 citations
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March 2014 in “Journal of Family Planning and Reproductive Health Care” PCOS is a common hormonal disorder in women, marked by high androgen levels and often seen in 20% of women via ultrasound.
11 citations
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August 2000 in “Journal of Endocrinology” DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.
1 citations
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January 2015 in “Elsevier eBooks” Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.
25 citations
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June 2023 in “Biomedicines” Men generally face more severe COVID-19 outcomes than women, partly due to hormonal differences.
21 citations
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April 2010 in “Pediatrics in Review” Delayed puberty affects some teens, and early treatment with hormones can help improve their growth and social well-being.
1231 citations
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May 2001 in “Hypertension” Men generally have higher blood pressure than premenopausal women, but postmenopausal women's blood pressure can surpass men's, and hormone therapy doesn't significantly help.
13 citations
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May 2007 in “Journal of Endocrinology” Synthetic 19-norprogestins promote bone cell growth and function through their non-phenolic metabolites.
3 citations
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July 2018 in “JAAPA” Some birth control pills can cause hair loss, and switching to ones with less androgen should help.
January 2026 in “Immunological Reviews” Females generally have stronger immune responses than males due to the X chromosome.
3 citations
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February 2005 in “Aktuelle Dermatologie” Prolactin and TGF-β receptor blockers might help treat hair loss.
5 citations
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August 2012 in “Journal of Dermatology” Tamoxifen may cause female hair loss by increasing androgen receptor expression.
28 citations
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August 2000 in “Current Opinion in Chemical Biology” Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.