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Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

Transgender men on testosterone therapy need ongoing gynecologic care due to potential cancer risks.

The letter suggests testosterone replacement therapy might worsen COVID-19 outcomes.

Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.

Finasteride may increase stroke risk in people with clotting tendencies.

PRP therapy may help with ovarian issues and fertility, but more research is needed.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

A male patient developed frontal fibrosing alopecia after antiandrogen therapy for prostate cancer.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Finasteride helps reduce heart issues and improves heart function.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Careful medical care is needed for those over 50 on hormone therapy during COVID-19.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Androgen therapy might help some women with low libido, but it has risks and should be used carefully.

Estrogen helps prevent artery plaque by stopping monocyte capture in blood vessels.

Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

Activating ER-β, not ER-α, improves skin cell growth and wound healing.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).