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60-90 / 1000+ resultsresearch First-in-human phase 1 study of ETC-159 an oral PORCN inhbitor in patients with advanced solid tumours.
ETC-159 was safe up to 30 mg, but no tumor shrinkage was seen.
research Insulin Resistance, Hyperandrogenism, and Its Associated Symptoms Are the Precipitating Factors for Depression in Women With Polycystic Ovarian Syndrome
Depression in women with Polycystic Ovarian Syndrome (PCOS) is linked to insulin resistance and hyperandrogenism, and managing these can help reduce depression. Lifestyle changes and Cognitive Behavioral Therapy can be effective treatments.
research National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2
The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.
research Effect of disulfide bonds in human hair fibers on the melting behavior of their crystalline structure
Disulfide bonds affect the melting behavior of hair's crystalline structure, but hair retains some stability even after these bonds are broken.
research Development and evaluation of polyherbal formulation for hair growth–promoting activity
The herbal formulation promoted hair growth faster and more effectively than minoxidil in rats.
research Skin Penetration and Permeation Properties of Transcutol® in Complex Formulations
Transcutol® helps drugs penetrate the skin more effectively in various formulations.
research Effects of Russelia equisetiformis methanol and aqueous extracts on hepatic function indices
Russelia equisetiformis extracts can harm liver function.
research Disulfide Cross-Linked Network Structure of Intermediate Filament and Matrix in Hair and Wool Cortices
Hair and wool strength is affected by the number and type of bonds in their protein structures, with hair having more protein aggregates than wool.
research Effect of ethanolic extract of Hibiscus rosa sinensis L., flowers onhair growth in female wistar rats
Hibiscus flower extract slowed down hair growth in rats.
research Future Directions in the Treatment of Vitiligo
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
research Evaluation of Hair Growth Activity of Buxus wallichiana Baill Extract in Rats
Buxus wallichiana extract improves hair growth and has antioxidant properties, with oral use more effective than topical.
research Determination of finasteride in human plasma by liquid chromatography–electrospray ionization tandem mass spectrometry with flow rate gradient
Researchers developed a quick and sensitive way to measure finasteride in blood using a small sample size.
research News Review: Lipid Technology 5/2014
New cleaning surfactants, biofuel production plans, dairy expansions, improved lipid testing methods, and various product launches and developments were reported in lipid technology.
research Evaluation of Biochemical and Hematological Parameters in Polycystic Ovarian Syndrome Among Urban College Girls
Polycystic Ovarian Syndrome is common in overweight urban college girls and may increase the risk of heart and metabolic problems.
research Chemically Induced Hair Loss/Alopecia
Some chemicals and drugs can cause hair loss, which usually grows back after stopping the treatment.
research Formulation and in vitro assessment of minoxidil niosomes for enhanced skin delivery
Niosomes improve minoxidil skin delivery for hair loss treatment.
research Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells
Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
research Enhancement of follicular delivery of finasteride by liposomes and niosomes
Liposomes and niosomes improve finasteride delivery for hair loss treatment.
research Degradation of Human Hair by Papain
Papain and bisulfite break down human hair by dissolving parts of it.
research Non-Edg family LPA receptors: the cutting edge of LPA research
New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.
research Structural Study of Polymorphs and Solvates of Finasteride
Different forms of hair loss drug can improve effectiveness.
research FOLLICULAR LIPOSOMAL DELIVERY SYSTEMS
New liposomal formulations may improve delivery of treatments to hair follicles, potentially helping with hair loss.
research Fullerene nanomaterials potentiate hair growth
Fullerene nanomaterials help hair grow faster and increase hair follicles.
research Profile of the progesterone derivative chlormadinone acetate — Pharmocodynamic properties and therapeutic applications
Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.
research Sex hormone-binding globulin and saliva testosterone levels in men with androgenetic alopecia
Men with hair loss have lower SHBG and higher saliva testosterone levels, suggesting increased androgen activity.
research Waterborne polyurethanes from castor oil-based polyols for next generation of environmentally-friendly hair-styling agents
Castor oil-based polyurethanes are promising for making safe, strong-performing, eco-friendly hair-styling products.
research Drug repositioning using in silico compound profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Targeted transfollicular delivery of artocarpin extract from Artocarpus incisus by means of microparticles
Microparticles containing artocarpin extract could effectively treat hair loss and acne with minimal side effects.
research Experimental, molecular docking investigations and bioavailability study on the inclusion complexes of finasteride and cyclodextrins
Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.