April 2019 in “Journal of Investigative Dermatology” Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.
February 2014 in “PubMed” Effective treatments exist only for certain types of hair loss, and many hair loss treatments do not guarantee significant improvement.
June 2001 in “Annals of Internal Medicine” The document concludes that more research is needed on the hepatitis B vaccine's side effects and the effectiveness of certain treatments for specific diseases.
July 1976 in “Archives of Dermatology” The document suggests more research is needed to understand skin conditions related to toothpaste and other treatments.
March 2024 in “CRC Press eBooks” Hair restoration surgery has greatly improved since ancient times.
January 2013 in “Revista Clínica Española” A postmenopausal woman's increased male hormone levels were successfully treated with surgery.
618 citations
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January 2018 in “Cochrane Database of Systematic Reviews” Selenium supplements do not prevent cancer and may increase certain health risks.
550 citations
,
January 2012 in “Oxford University Research Archive (ORA) (University of Oxford)” Lithium can cause some health issues, but severe risks are low.
505 citations
,
October 2011 in “Journal of clinical oncology” MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
407 citations
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January 2008 in “Cochrane Database of Systematic Reviews” Glucocorticoid corticosteroids improve muscle strength in Duchenne muscular dystrophy but can cause side effects.
335 citations
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March 2004 in “Development” Temporary activation of β-catenin can create new hair follicles, but ongoing activation is needed to keep hair follicle tumors.
305 citations
,
December 2000 in “The EMBO Journal” Inhibiting Bmp signaling disrupts hair growth and differentiation.
191 citations
,
February 2002 in “Archives of Dermatology” Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.
179 citations
,
March 2005 in “British Journal of Dermatology” Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.
139 citations
,
October 2005 in “Journal of Investigative Dermatology” The nail matrix has a reduced immune response, protecting it from autoimmunity.
138 citations
,
October 2012 in “Behavioral Ecology” Masculine facial features may not reliably indicate heritable health, and more research is needed.
131 citations
,
July 2009 in “Experimental Dermatology” The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
127 citations
,
June 2008 in “British Journal of Clinical Pharmacology” Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
127 citations
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July 2002 in “EMBO journal” Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
125 citations
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September 2001 in “The FASEB Journal” Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.
110 citations
,
January 1984 in “Progress in brain research” Gonadal hormones may influence sex differences in play fighting in animals, but their effect on human spatial behavior is unclear and needs more research.
98 citations
,
December 2008 in “Journal of Investigative Dermatology” Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.
91 citations
,
April 2011 in “Journal of Ethnopharmacology” Polygonum multiflorum extract helps grow hair by activating certain hair growth signals in mice.
91 citations
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July 2004 in “BMJ. British medical journal” The document concludes that molluscum contagiosum is a common, benign skin infection in children, often healing without scarring.
87 citations
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December 2015 in “Cochrane library” No single treatment is clearly effective for central serous chorioretinopathy.
73 citations
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November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Some women with common hair loss may develop permanent hair loss.
71 citations
,
January 2011 in “Journal of cutaneous pathology” A rare skin condition was confirmed to be associated with a specific virus in a young girl.
62 citations
,
March 2008 in “American Journal of Human Genetics” Hair loss gene found on chromosome 3q26.
58 citations
,
July 1974 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Cyproterone acetate combined with ethinyl estradiol significantly reduced hirsutism in women.
56 citations
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July 2020 in “Journal of Dermatological Treatment” Azelaic acid is safe and effective for treating rosacea and other skin issues.