43 citations
,
August 2010 in “Expert Opinion on Investigational Drugs” Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
28 citations
,
July 2022 in “Endocrine” Low prolactin in young women may increase heart and metabolism risks.
13 citations
,
December 2016 in “Journal of Cosmetic Dermatology” Oxidative stress increases in early hair loss, and family history plays a role; antioxidants may help future treatments.
11 citations
,
January 2024 in “Indian Journal of Pharmaceutical Sciences” Phytosomes improve the body's absorption of plant extracts for better health benefits.
11 citations
,
March 2008 in “Experimental Dermatology” A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.
7 citations
,
September 2024 in “Scientific Reports” Sebum samples remain stable under various storage conditions, making them suitable for remote and at-home testing.
July 2022 in “Research Square (Research Square)” Lower PPARγ levels and specific gene variations are linked to more severe Frontal Fibrosing Alopecia.
January 2015 in “Elsevier eBooks” Nanocarriers like liposomes and cyclodextrins improve how angiotensin-(1-7) is delivered in the body.
42 citations
,
March 2018 in “PLOS Biology” Autophagy is important for human hair growth and health.
183 citations
,
January 1987 in “British Journal of Anaesthesia” Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.
166 citations
,
March 2007 in “Hypertension” High androgen levels in young women with PCOS are linked to higher blood pressure.
114 citations
,
October 2009 in “Gastroenterology” Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.
30 citations
,
November 2018 in “Fertility and Sterility” Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.
21 citations
,
July 2016 in “Gynecological Endocrinology” Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.
11 citations
,
January 2013 in “Postępy Dermatologii i Alergologii” The conclusion is that a combination of noninvasive treatments and lifestyle changes can improve skin health during menopause.
4 citations
,
January 1987 in “Annual reports in medicinal chemistry” New treatments for skin diseases are more effective and patient-friendly, but many still lack a cure.
1 citations
,
November 2008 in “Acta crystallographica” Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.
February 2024 in “Journal of Health Science and Medical Therapy” ADAM17 could be a potential target for treating PCOS.
December 2014 in “Annals of psychophysiology” Power-enhancing drugs can cause mood swings, aggression, anxiety, and physical side effects, questioning their overall benefits.
June 2001 in “International Journal of Cosmetic Surgery and Aesthetic Dermatology” Finasteride improves hair growth in men with androgenetic alopecia.
81 citations
,
May 2007 in “Fertility and Sterility” Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
855 citations
,
June 2009 in “The Journal of Clinical Endocrinology & Metabolism” The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.
249 citations
,
November 2003 in “Clinical endocrinology” Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
166 citations
,
October 2018 in “Endocrine Reviews” Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.
165 citations
,
September 2003 in “Toxicology and applied pharmacology” Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
137 citations
,
June 2005 in “Climacteric” Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.
132 citations
,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
124 citations
,
March 2012 in “JAMA” Testosterone's muscle-building effects do not require its conversion to DHT.
111 citations
,
March 2012 in “Expert Opinion on Drug Delivery” Liposomes could improve how skin care products work but are costly and not very stable.
108 citations
,
December 2003 in “Lasers in surgery and medicine” ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.