research The genetic evolution of skin squamous cell carcinoma: tumor suppressor identity matters
The type of tumor suppressor gene lost affects the behavior of skin cancer.
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870-900 / 1000+ resultsresearch Dermal lymphatic dilation in a mouse model of alopecia areata
Mice with alopecia areata had wider lymphatic vessels in their skin.
research Constitutive activation of S tat3 in mouse epidermis is linked to hair deficiency and cytoskeletal network damage
Overactive Stat3 in mouse skin causes hair loss and cell structure damage.
research New developments in our understanding of acne pathogenesis and treatment
We now understand more about what causes acne and this could lead to better, more personalized treatments.
research Is there a ‘gut–brain–skin axis’?
Probiotics may help reduce stress-related skin issues and improve hair growth.
research Chemistry42: An AI-Driven Platform for Molecular Design and Optimization
Chemistry42 effectively creates and optimizes new molecules for drug discovery.
research The role of PPARγ-mediated signalling in skin biology and pathology: new targets and opportunities for clinical dermatology
PPARγ is crucial for skin health but can have both beneficial and harmful effects.
research Endogenous neurosteroids modulate epileptogenesis in a model of temporal lobe epilepsy
Neurosteroids may help prevent seizures in epilepsy.
research Prostanoid receptors in anagen human hair follicles
Human hair follicles contain a complex network of prostanoid receptors that may influence hair growth.
research Recent advances in understanding the role of the skin microbiome in the treatment of atopic dermatitis
The skin microbiome plays a key role in treating atopic dermatitis.
research A “hair‐raising” history of alopecia areata
The document concludes that understanding and treatments for alopecia areata have significantly advanced, now recognizing it as an autoimmune disorder.
research Can we teach old drugs new tricks?—Repurposing of neuropharmacological drugs for inflammatory skin diseases
Old neuropharmacological drugs might be effective for treating inflammatory skin diseases.
research Does maternal exposure to artificial food coloring additives increase oxidative stress in the skin of rats?
Maternal exposure to artificial food coloring may increase skin disease risk in rat offspring.
research The Effect of Hydration on the Mechanical Behaviour of Hair
research Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis
Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.
research Hidradenitis suppurativa: A folliculotropic disease of innate immune barrier dysfunction?
Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.
research Targeting the Hippo/YAP /TAZ signalling pathway: Novel opportunities for therapeutic interventions into skin cancers
Blocking YAP/TAZ could be a new way to treat skin cancer.
research Tissue fibrosis associated depletion of lipid‐filled cells
Fibrosis causes loss of important fat cells, affecting tissue function.
research The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2
A special receptor in sensory nerve endings helps control how they respond to stretching.
research Simultaneous Determination of Selected Steroids with Neuroactive Effects in Human Serum by Ultrahigh-Performance Liquid Chromatography–Tandem Mass Spectrometry
A new method accurately measures nine neuroactive steroids in small blood samples, helping to study brain diseases.
research Pregnenolone for the treatment of L-DOPA-induced dyskinesia in Parkinson's disease
Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.
research Viewpoint 1
Hidradenitis suppurativa is a complex, non-infectious skin condition with no single cause, difficult to treat, and greatly affects quality of life.
research JUNB affects hair follicle development and regeneration by promoting the proliferation of dermal papilla cells in goat
JUNB boosts hair growth in goats by helping specific skin cells multiply.
research Fundamental research on the action mechanism of the 800 nm semiconductor laser on skin blackheads and coarse pores
Low-dose 800 nm laser effectively treats blackheads and coarse pores without harming cell growth.
research Analysis of changes in microRNA expression profiles in response to the troxerutin-mediated antioxidant effect in human dermal papilla cells
research Metabolic and Vascular Inflammation in Alopecia Areata: Linking Uric Acid, Lipid Imbalance and ICAM ‐1 Upregulation
Improving blood vessel health and controlling uric acid may help manage alopecia areata.
research Follicular unit extraction method of hair transplantation: Technique, advantages and limitations
The follicular unit extraction method for hair transplants is a technique with benefits and drawbacks.
research Intraretinal variation in disease severity in the Oat mouse model of gyrate atrophy
The Oat mouse model shows mild retinal degeneration, useful for testing treatments.
research PandaOmics: An AI-Driven Platform for Therapeutic Target and Biomarker Discovery
PandaOmics uses AI to find new disease treatment targets and biomarkers.
research Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis
Loss of a specific protein in skin cells causes symptoms similar to psoriasis.