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August 2024 in “Nature Communications” Quiescent cells have increased mitochondrial activity and ECM gene expression, but reduced glycolysis.
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March 2024 in “Genes & Diseases” EBF1 controls hair type and length.
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July 2007 in “Journal of cell science” Miz1 is essential for proper hair structure and growth.
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August 2023 in “Nature communications” Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
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July 2023 in “Inflammation and Regeneration” ALKBH5 helps wounds heal faster by stabilizing PELI2 mRNA.
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January 2013 in “genesis” Zfp157 is active in many mouse tissues during development and in specific adult cells.
November 2024 in “Journal of Investigative Dermatology” Bimekizumab quickly improves psoriasis symptoms and skin at the molecular level.
ETS2 is crucial in squamous cell carcinoma development and could be a therapeutic target.
Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.
ETS2 drives cancer progression in squamous cell carcinoma and is linked to poor patient outcomes.
226 citations
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August 2006 in “Molecular and Cellular Biology” EGF signaling affects gene expression in skin cells, influencing hair growth and potentially cancer.
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October 2019 in “International Journal of Dermatology and Venereology” Zebrafish help understand genetic causes of skin pigment disorders like albinism.
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May 2012 in “Cell Adhesion & Migration” ILK and ELMO2 help cells move and stick together, important for wound healing and hair growth.
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April 2020 in “Frontiers in Oncology” EMT and metabolic pathways help cancer cells resist treatment and spread.
January 2025 in “Frontiers in Cell and Developmental Biology” Hox proteins help maintain keratinocyte identity by regulating miRNA expression.
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February 2023 in “Transgenic Research” The E2 protein affects gene activity in hair follicles of mice.
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June 2023 in “The FASEB journal” LSD1 and HSP90 help heal skin wounds by changing hair follicle stem cells' metabolism.
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March 2016 in “Frontiers in Plant Science” Spermidine is essential for plant growth and adaptation to stress.
December 2021 in “Journal of Investigative Dermatology” Neutrophils quickly move to the site of skin injury.
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February 2024 in “Matrix Biology” 29 citations
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February 2001 in “Proceedings of the National Academy of Sciences” A specific DNA region controls skin cell gene expression by working with certain proteins.
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March 2016 in “Developmental Cell” Zebrafish skin regeneration relies on cell behaviors and reactive oxygen species, with antioxidants reducing and hydrogen peroxide increasing regeneration.
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July 2015 in “EMBO Reports” Tmem50b and 2610305D13Rik genes play key roles in early mouse embryo development.
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July 2005 in “Experimental dermatology” The fuzzy gene is crucial for controlling hair growth cycles.
February 2025 in “Journal of Investigative Dermatology” The ZIP13 variant is linked to abnormal hair quality.
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July 2025 in “Nature Communications” Piezo1 helps skin grow by managing metabolism and inflammation.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.
March 2026 in “Calcified Tissue International” The EDA pathway plays a key role in bone development by interacting with other signaling pathways.
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September 2019 in “Journal of Cellular Physiology” Akt2 protein is essential for normal cell division in early mouse embryos.
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May 1998 in “Genes & Development” Ets2 gene is crucial for placental development in mice.