August 2016 in “Journal of Investigative Dermatology” Some men don't respond to common hair loss treatments, but a new inhibitor, FOL-005, shows promise for targeting unwanted hair growth.
18 citations
,
August 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Two existing drugs may help treat COVID-19 by inhibiting a key viral protein.
31 citations
,
September 2008 in “International Journal of Andrology” 5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
4 citations
,
May 2019 in “Sultan Qaboos University Medical Journal” Tofacitinib helped regrow hair in a patient with severe hair loss and improved their quality of life without side effects.
July 2024 in “The Egyptian Journal of Hospital Medicine” 34% of patients on hepatitis C treatment had reversible skin issues.
16 citations
,
February 2010 in “Journal of the European Academy of Dermatology and Venereology” Fibrosing alopecia in a pattern distribution is a unique hair loss condition that may respond to antiandrogen therapy.
4 citations
,
January 2023 in “Marine Drugs” Marine compounds from gorgonians and soft corals show promise for drug development, especially for chronic disorders.
219 citations
,
October 2009 in “Steroids” 5α-reductase inhibitors, like Finasteride and Dutasteride, help manage benign prostatic hyperplasia.
5 citations
,
February 1997 in “Bioorganic & Medicinal Chemistry” New compounds were made that effectively block a specific enzyme related to androgen conditions.
22 citations
,
June 2011 in “Acta Ophthalmologica” Certain medications like α1-blockers, benzodiazepines, and finasteride increase the risk of floppy iris syndrome during cataract surgery.
September 2025 in “Journal of the American Academy of Dermatology” Some JAK inhibitors are effective for significant hair regrowth in alopecia areata.
3 citations
,
June 1983 in “Archives of Dermatology” Aminopterin effectively improves skin conditions but has toxic side effects that need careful monitoring.
1 citations
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September 2022 in “BioNanoScience” Tofacitinib can help hair grow back in alopecia patients but hair loss might return if the dose is lowered.
5 citations
,
July 2007 in “PubMed” An HIV patient's complete hair loss was reversed after switching from lopinavir/ritonavir to nelfinavir.
August 2015 in “Dermatología Argentina” Frontal fibrosing alopecia causes hairline recession and eyebrow loss in postmenopausal women.
December 2025 in “npj Breast Cancer” Capivasertib improves survival in certain breast cancer cases but requires careful management of side effects.
Baricitinib is more effective than tofacitinib for hair regrowth in alopecia patients.
26 citations
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June 2018 in “Australasian Journal of Dermatology” Stopping sunscreen use on the forehead led to hair regrowth in a woman with frontal fibrosing alopecia.
February 2025 in “PubMed” CS12192 effectively treats alopecia areata with better safety than current options.
June 2020 in “Journal of Drugs in Dermatology” Frontal fibrosing alopecia can be misdiagnosed as androgenetic alopecia in African American women.
20 citations
,
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Six existing drugs may help block virus entry in COVID-19.
1 citations
,
October 2020 in “Journal of Cosmetic Dermatology” Using minoxidil and tofacitinib together can effectively treat severe hair loss.
9 citations
,
January 2020 in “Postepy Dermatologii I Alergologii” Frontal fibrosing alopecia is a poorly understood condition with increasing cases and unclear treatment effectiveness.
Arabidopsis Formin 2 stabilizes actin filaments to aid cell-to-cell trafficking.
20 citations
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January 2014 in “Journal of the European Academy of Dermatology and Venereology” The critique highlights an error in a review about hair loss treatment, stressing the need for accurate information and caution due to poor evidence quality.
April 2016 in “Journal of Investigative Dermatology” MEK and BRAF inhibitors increase sebum production and accumulation, which could cause acne-like side effects.
February 2021 in “Reactions Weekly” Finasteride and dutasteride may cause macular abnormalities.
18 citations
,
July 2008 in “Current Oncology Reports” EGFR cancer drugs often cause a rash, which can lead to distress and isolation, but may also improve outcomes for some cancer patients. Current treatments for the rash are limited, but a compound called menadione shows promise.
March 2014 in “The Journal of Urology” Finasteride increases CD8+ T cells in BPH tissues.
2 citations
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September 2021 in “Anais Brasileiros de Dermatologia” Increased sunscreen use may be linked to frontal fibrosing alopecia in Hispanic females.