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Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Ultrasound measurement of the ovarian stroma to total area ratio is not a reliable single predictor of high male hormone levels in Thai women with PCOS, but works better when combined with clinical signs.

Managing emotional distress, obesity, insulin resistance, and high male hormones is crucial for improving well-being in women with PCOS.

Hormonal therapy is a good option for women with severe acne, especially when there's a chance of hormone imbalance.

A specific gene variant is linked to severe insulin resistance and hormone imbalance in a teenage girl.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

Men's fertility and sexual health decline with age, with reduced testosterone and virility, and many lose fertility by their eighties.

Women with PCOS may have a higher risk of respiratory and ear infections due to slower nasal mucociliary clearance.

The piRNA pathway genes are crucial in early development and may influence sex differentiation through hormone regulation.

Androgenetic alopecia is linked to insulin resistance and hormonal imbalances.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.

Gender-affirming hormone therapy affects health risks and requires careful management, especially as transgender individuals age.

Athletic trainers should understand and support the medical needs of transgender and gender-diverse patients.

Care for gender-dysphoric Veterans can be improved with a consistent, team-based approach.

Women with schizophrenia on atypical antipsychotics are more likely to have polycystic ovarian syndrome (PCOS) than women without schizophrenia.

Women may need different blood pressure guidelines than men for heart disease prevention.

Females have stronger immune responses to COVID-19 than males, leading to better outcomes.

Older men with low levels of a testosterone byproduct had a higher chance of developing an irregular heartbeat.

High androgen levels cause skin issues in PCOS, affecting quality of life.

Dihydrotestosterone boosts inflammation in fat cells more than testosterone.

PCOS can cause excess hair growth, oily skin, hair loss, acne, and dark skin patches.

COC treatment improves hormone and metabolic levels in PCOS patients.

Menopause causes skin and hair to become drier and thinner, but hormone therapy can improve these conditions.

New understanding of hair loss could lead to better treatments.

Losing weight, possibly through bariatric surgery, is key to improving PCOS and hyperandrogenism symptoms in obese patients.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

High uric acid levels are more common in PCOS patients, especially those with androgenic PCOS, and are linked with increased cardiovascular risk and other metabolic issues.