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17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Gender-affirming hormone therapy changes hair growth in transgender people, with feminizing therapy reducing hair and masculinizing therapy increasing it, but sometimes additional treatment is needed.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

A man's rare adrenal tumor caused feminization and white hair, was removed surgically, and improved after treatment.

Gender-affirming hormone therapy affects health risks and requires careful management, especially as transgender individuals age.

Feminizing hormone therapy increases kidney filtration rate.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

The document concludes that respectful, gender-affirming healthcare improves mental health and encourages continued medical care for transgender and non-binary individuals.

Cyproterone acetate is a safe treatment that causes mild feminizing effects in adolescent trans-girls.

Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.

Hormone therapy increases facial and body hair in transgender men, while hair removal improves well-being in transgender women, but cost is a barrier as insurance often doesn't cover it. Dermatologists can use various treatments for these hair issues.

Most transgender patients getting laser hair removal before gender-affirming surgery are already on hormone therapy, which might affect the hair removal process.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Gender-affirming hormone therapy in South Korea aligns with international guidelines and has specific side effects.

Androstenedione, a hormone supplement, doesn't improve muscle or performance and can cause harmful side effects.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Estrogen therapy can help stabilize the hairline in transfeminine individuals.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.

Dermatologists are essential in helping transgender and gender diverse patients with skin and hair issues related to gender affirmation and hormone therapy.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Oestrogens are key for bone growth during puberty in both boys and girls.

Forehead modification greatly increases the perception of femininity and is a safe procedure.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Finasteride and minoxidil together promote hair growth better than either alone.

Hormonal therapy for transgender individuals carries health risks but is a personal choice.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.

Many children and teens referred to gender services receive hormone treatments, but more research is needed on their long-term care and outcomes.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.