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The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Androgens affect the function and health of the endometrium.

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

Finasteride treatment lowers urine androgen and prostaglandin levels, making them potential markers for effectiveness.

Androgens increase pigmentation in young hamsters, but estrogens can reverse this effect.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Testosterone pellets might work for transgender men's hormone therapy, but more research is needed.

Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.

Finasteride can cause serious physical, mental, and sexual side effects, even after stopping the treatment.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Finasteride caused enlarged breast tissue in a 62-year-old man.

Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.

Finasteride may cause vitiligo, sexual issues, and depression; better treatments and predicting side effects needed.

A woman's masculine features were caused by a rare ovarian tumor that produced male hormones.

Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.

Antiandrogen therapy may be beneficial for women with hidradenitis suppurativa.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.

A combination of desogestrel and ethinyl oestradiol effectively reduces hair growth in hirsute women.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

Social rejection can harm long-term mental health in transgender individuals.

Hormonal therapy in adults with gender dysphoria often leads to skin issues like acne, requiring a team of skin and hormone doctors.

Adults with gender dysphoria on hormone treatment often have skin problems like acne, which are common but not always recognized.

The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.

Skin hormone levels change significantly after menopause.

Care for gender-dysphoric Veterans can be improved with a consistent, team-based approach.

Finasteride has various adverse effects, including sexual dysfunction and mental health issues, which vary by age and gender.