research Estro-progestogen combinations: Effect on sex Steroid Binding Protein (SBP) synthesis
Certain hormone treatments can increase SBP levels and help with mild body hair growth.
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research The efficacy and use of finasteride in women: a systematic review
Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.
research Die Menopause und ihre Auswirkungen auf Haut und Haare
Menopause causes skin and hair to become drier and thinner, but hormone therapy can improve these conditions.
research The effects of SM-215 on androgeneticalopecia
SM-215 was found to be effective in treating male pattern baldness.
research Pharmacology of Anti-androgens in the Skin
Anti-androgens can help reduce the effects of male hormones on the skin.
research Adverse Effects and Safety of 5-alpha Reductase Inhibitors (Finasteride, Dutasteride): A Systematic Review.
5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.
research Phase-specific differential regulation of mechanical allodynia in a murine model of neuropathic pain by progesterone
Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.
research Exogenous testosterone, finasteride and castration effects on testosterone, insulin, zinc and chromium in adult male rats.
Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.
research Author response for "Repeated finasteride administration promotes synaptic plasticity and produces antidepressant‐ and anxiolytic‐like effects in female rats"
research Wider clinical applications of fumaric acid esters: A useful option in psoriasis patients with multiple sclerosis
Finasteride for hair loss in young men may significantly increase the risk of sexual dysfunction.
research 9 Role of 5α-reductase in health and disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
research Bicalutamide: A review
Bicalutamide may help treat female pattern hair loss.
research Safety concerns regarding 5α reductase inhibitors for the treatment of androgenetic alopecia
5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
research The effect of finasteride on the male rat brain
Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.
research Hair Cycle Control by Estrogens: Catagen Induction via Estrogen Receptor (ER)-α Is Checked by ERβ Signaling
Estrogen receptors affect hair growth, with ER beta slowing down the hair cycle changes caused by ER alpha.
research Finasteride
Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
research Facial minimally invasive aesthetic procedures and quality of life in transgender individuals: a prospective study
Facial aesthetic procedures improve quality of life for transgender individuals.
research Impact of Alpha Blockers, 5-alpha Reductase Inhibitors and Combination Therapy on Sexual Function
Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.
research The Interplay between Finasteride-Induced Androgen Imbalance, Endoplasmic Reticulum Stress, Oxidative Stress, and Liver Disorders in Paternal and Filial Generation
Finasteride in male rats causes liver and metabolic issues in their offspring.
research Characterization and Management of Androgenetic Alopecia in Transgender and Gender-Diverse Individuals: A Narrative Review
Personalized hair loss treatments are needed for transgender individuals, but more research is required.
research Widespread skin hypopigmentation caused by finasteride when used for female hirsutism
Finasteride can cause lasting skin lightening in women.
research Identification of xenobiotics interfering with 5 α -reductase (SRD5A2) activity
MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.
research 5alpha-reductase inhibitors - a new hope in dermatology?
Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.
research Finasteride in the treatment of female pattern (androgenic) alopecia: a case report and review of the literature.
Finasteride may effectively treat female pattern hair loss.
research Hormone Treatment for the Adult Transgender Patient
Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.
research Molecular Interactions of New Pregnenedione Derivatives
The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.
research Unilateral Gynecomastia Induced by Treatment With 1 mg of Oral Finasteride
Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.
research The influence of low dose finasteride, a type II 5α-reductase inhibitor, on circulating neuroactive steroids
Low dose finasteride decreases certain steroids, possibly increasing depression risk.
research Studies on Neurosteroids XXV. Influence of a 5.ALPHA.-Reductase Inhibitor, Finasteride, on Rat Brain Neurosteroid Levels and Metabolism
Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.
research Inhibitors of 5α-reductase-related side effects in patients seeking medical care for sexual dysfunction.
5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.