March 2026 in “Panacea Journal of Medical Sciences” The technique successfully reconstructed a functional neo-vagina with 100% survival and patency, but lacked mucus secretion.
1 citations
,
April 2024 in “Journal of Plastic Reconstructive & Aesthetic Surgery” 1 citations
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March 2005 in “Zentralblatt für Gynäkologie” A postmenopausal woman had high testosterone from her right adrenal gland, leading to recommended surgery.
October 2024 in “Journal of the Endocrine Society” Gender-affirming hormone therapy affects metabolism differently based on treatment type.
3 citations
,
January 2019 in “PubMed” Platelet-rich plasma may be effective for genital rejuvenation and deserves more research.
3 citations
,
August 2021 in “Journal of the American Academy of Dermatology” Facial hair is crucial for transgender men's gender identity and transition.
11 citations
,
November 2022 in “Journal of Endocrinological Investigation” Hormonal treatments can change hair and skin in transgender people, but may not fully achieve desired results.
7 citations
,
January 2019 in “Journal of clinical medicine research” Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.
October 2022 in “Springer eBooks” The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.
January 2024 in “JEADV clinical practice” Gender-affirming dermatology treatments generally improve mental well-being for transgender individuals, but more research is needed.
10 citations
,
April 2018 in “Facial Plastic Surgery” The surgical technique of scalp advancement and pretrichial brow lift shortens the forehead and lifts brows, is good for women and transgender women with high foreheads, but not recommended for men and has some risks.
January 2010 in “Springer eBooks”
June 2023 in “The journal of sexual medicine” The treatment helped a transgender woman stop drinking, improved her mental health, and reduced her gender dysphoria.
122 citations
,
July 1990 in “Teratology” Finasteride exposure in pregnancy causes genital abnormalities in male rats.
46 citations
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December 1992 in “The Journal of Steroid Biochemistry and Molecular Biology” Affected males are born with ambiguous genitalia, raised as females, but develop male traits at puberty due to enzyme deficiency.
January 2023 in “The Annals of african surgery” Hormone treatment before hypospadias surgery can increase penis size and reduce surgery complications.
86 citations
,
March 1993 in “Toxicology and Applied Pharmacology” Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.
January 2021 in “Case Reports” A 71-year-old woman developed male-like features due to high testosterone levels caused by a benign ovarian tumor, which was successfully removed by surgery.
27 citations
,
September 2017 Pubic hair transplantation can improve self-esteem in those with sparse pubic hair.
10 citations
,
May 2009 in “Cases Journal” A woman's masculine symptoms were caused by an ovarian tumor, which improved after surgery.
38 citations
,
May 1971 in “Clinical genetics” A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.
116 citations
,
December 2013 in “The Journal of Pediatrics” Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.
January 2018 in “Elsevier eBooks” 5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.
9 citations
,
January 2007 in “Endocrine Practice” A woman's male-like symptoms and high testosterone were due to ovarian hilus-cell hyperplasia, which improved after surgery.
3 citations
,
February 2021 in “JAMA Dermatology” Masculinizing hormone therapy increases the risk of hair loss in transgender and gender-diverse patients.
November 2021 in “Khyber Medical University Journal” A rare ovarian tumor caused a postmenopausal woman to develop male-like features, which improved after surgery.
1 citations
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April 2022 in “Indian Journal of Plastic Surgery” Hormone therapy greatly improves the quality of life for adults seeking gender reaffirmation, but more research is needed in India.
October 2022 in “Journal of the ASEAN Federation of Endocrine Societies” GnRH-a or orchiectomy is more effective than anti-androgens for managing hormone levels in transgender women.
November 2022 in “Journal of the Endocrine Society” A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.
94 citations
,
April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.