research Pharmacological Options for Treatment of Hyperandrogenic Disorders
Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.
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180-210 / 1000+ results research The biochemical and phenotypic characterization of females homozygous for 5 alpha-reductase-2 deficiency.
Females with 5 alpha-reductase-2 deficiency have less body hair, no acne, normal fertility, and delayed menarche.
research 5α Reductase Deficiency—a Rare Cause of Ambiguous Genitalia and Gender Dysphoria
5α-reductase deficiency can cause ambiguous genitalia and gender dysphoria, treatable with testosterone.
research Sequential estrogen-progestin addition to gonadotropin-releasing hormone agonist suppression for the chronic treatment of ovarian hyperandrogenism: a pilot study.
The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.
research [Long-term treatment of virilized women with cyproterone acetate (author's transl)].
Cyproterone acetate effectively treats virilized women, especially under 35, despite some side effects.
research Case Report: Successful Use of Minoxidil to Promote Facial Hair Growth in an Adolescent Transgender Male
Minoxidil can help transgender males grow facial hair before starting testosterone therapy.
research Gender-affirming hair procedures
Hair transplants help transgender patients look more like their gender identity, with different procedures for trans women and men.
research Facial Feminization Surgery/Gender Confirming Facial Surgery: Background and State of the Art
Facial feminization surgery helps make facial features more feminine, improving patient satisfaction and safety.
research Use of low-dose oral minoxidil for hair growth in transgender and gender non-binary adult patients: a retrospective cohort study
research Evaluating the psychosocial impact of gender‐affirming dermatology treatments: A systematic review
Gender-affirming dermatology treatments generally improve mental well-being for transgender individuals, but more research is needed.
research Antiandrogenic progestins for treatment of signs of androgenisation and hormonal contraception
Certain hormone medications can treat symptoms like acne and unwanted hair, regulate periods, and prevent pregnancy in women and teenage girls.
research Two Transgender Men Receiving Subdermal Testosterone Pellets for Gender Affirmation
Testosterone pellets might work for transgender men's hormone therapy, but more research is needed.
research Steroid 5α-Reductase Inhibitors
New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
research Managing Dermatologic Effects of Gender-Affirming Therapy in Transgender Adolescents
Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.
research Abstract: Facial Feminization Surgery: Effectiveness, Optimization of the Process and Complications
Facial Feminization Surgery is effective and safe, with minimal complications.
research Nipple Differentiation in Fetal Male Rats Treated with an Inhibitor of the Enzyme 5α-Reductase: Definition of a Selective Role for Dihydrotestosterone*
Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.
research Hair Restoration in the Gender-Affirming Patient
Hair restoration helps transgender patients achieve desired gender appearances.
research Women Also Use 5α-Reductase Inhibitors—Reply
Women also use 5α-reductase inhibitors, and their effects differ from men.
research More about X‐linked testicular feminization of the mouse as a noninducible (is) mutation of a regulatory locus: 5α‐androstan‐3α‐17ß‐diol as the true inducer of kidney alcohol dehydrogenase and ß‐glucuronidase
A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.
research Clinical effects of cross-sex hormone therapy in adult trans persons
research Dermatologic care of the transgender patient - eScholarship
Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.
research SAT645 Cardiac Autonomic Modulation In Transgender Men Under Gender-affirming Hormone Therapy
Testosterone treatment may affect heart response to stress in transgender men.
research 5alpha-reductase inhibitors/finasteride.
research Understanding and Addressing Hair Disorders in Transgender Individuals
Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.
research Differential Suppression of Testosterone and Estradiol in Hirsute Women With the Superactive Gonadotropin-Releasing Hormone Agonist Leuprolide*
Leuprolide effectively reduces hair growth in hirsute women at higher doses.
research MALE PSEUDOHERMAPHRODITISM DUE TO 17β-HYDROXYSTEROID DEHYDROGENASE DEFICIENCY: STUDIES ON THE NATURAL HISTORY OF THE DEFECT AND EFFECT OF ANDROGENS ON GENDER ROLE
Masculinization in affected individuals occurs gradually after puberty due to hormone changes.
research [Systematic treatment with sex hormones in dermatology].
Sex hormone therapy is effective for certain skin conditions like acne and seborrhea, but less so for female hair loss and excessive hair growth.
research Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors
Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.
research [Ovulation inhibition in the treatment of androgenic alopecia in woemn].
research Estranys matins de febrer: Pauline Fondevila
Trienones are more effective at inhibiting the enzyme linked to hair loss than dienones.