research Inhibition of 5α‐Reduced Steroid Biosynthesis Impedes Acquisition of Ethanol Drinking in Male C57BL/6J Mice
Finasteride reduces alcohol consumption in mice by affecting brain chemicals.
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research Novel iron oxide nanocarriers loading finasteride or dutasteride: Enhanced skin penetration for topical treatment of alopecia
Iron oxide nanoparticles improve skin penetration and drug release for hair loss treatment.
research Characterization of follicular minoxidil sulfotransferase activity in a cohort of pattern hair loss patients from the Indian Subcontinent
About 41% of Indian hair loss patients have low enzyme activity that affects hair loss treatment effectiveness, with men affected more than women. Testing for this can guide treatment.
research Abstracts: Reduction‐induced surface modification of human hair
Chemical treatments change hair surface properties, making it more hydrophilic and able to bind conditioners.
research Cost-effectiveness analysis of laboratory monitoring in newly diagnosed telogen effluvium patients
Targeted testing for telogen effluvium patients can save healthcare costs.
research The Role of Micronutrients and Thyroid Function Tests in Pediatric Hair Loss
Low zinc and folate levels are linked to hair loss in children.
research Can a glycated hair protein assay be a non-invasive indicator of blood glucose control? - Assessing the influence of sample mass and chemical hair treatments
Hair glycation could be a reliable non-invasive indicator of blood glucose control, but its use is limited by factors like sample collection and hair treatments.
research Characterization of response of murine hair follicle-derived keratinocyte against androgen and testosterone 5α-redactase activity
Mouse hair cells respond to male hormones by growing less, and this can be stopped by certain blockers.
research Dermal papilla cells-conditioned medium attenuates oxidative stress-induced senescence via ferroptosis inhibition
Dermal papilla cell-conditioned medium can help reduce skin aging caused by oxidative stress.
research Image 4_Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced alopecia areata.tif
Targeting specific metabolic and ionic pathways may improve alopecia areata treatment.
research Tentative reference ranges for calcium and strontium in Spanish children’ scalp-hair.
Girls in Alcalá have higher hair calcium and strontium levels than boys, with lower overall levels than other regions.
research Obstructive sleep apnea, low transferrin saturation levels, and male‐pattern baldness
Men with sleep apnea and low iron levels are more likely to have male-pattern baldness, especially if they have a family history of hair loss.
research Rapid determination of minoxidil in human plasma using ion-pair HPLC
Quick method to measure minoxidil in blood, accurate and useful for labs.
research Finasteride: A slow-binding 5.alpha.-reductase inhibitor
Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.
research 1424 METHYLATION AND DECREASED EXPRESSION OF 5-ALPHA REDUCTASE 2 IN HUMAN PROSATE SAMPLES: IMPLICATIONS FOR RESISTANCE TO THERAPY FOR BPH
Methylation of the 5-AR2 gene may cause resistance to Finasteride in BPH patients.
research Low Free Thyroxine (FT4) in critically ill juvenile systemic lupus erythematosus: a diagnostic approach
Low free thyroxine (FT4) is common in young lupus patients and needs quick diagnosis and treatment.
research 5α-reductase activity in women with polycystic ovary syndrome: a systematic review and meta-analysis
Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.
research Zinkkonzentration des Rattenhaares bei Zink-Depletion und -Repletion
Hair zinc levels don't reliably indicate overall zinc status in animals.
research AB032. Development of new treatment modality for male infertility by using phytopharmaceuticals
MOTILIPERM may help treat male infertility by reducing stress in cells.
research Anemia na COVID longa: características e correlações clínicas
Long COVID can cause anemia and iron issues, leading to fatigue and slow recovery, especially in men and severe cases.
research Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers*
Finasteride safely lowers DHT levels without affecting testosterone.
research Simultaneous RP-HPLC-DAD determination of dansyl amino acids in chemically treated human hair
A new method accurately measures amino acids in treated hair, showing bleaching reduces amino acids while protein treatments increase them.
research Hair and Serum Copper, Zinc, Calcium, and Magnesium Concentrations in Alzheimer‐type Dementia
Mineral levels in hair and serum don't help diagnose Alzheimer's.
research Chronic telogen effluvium in women: role of micronutrients, a case–control study in north of Iran
The study concluded that low iron and vitamin D levels in women might play a role in chronic hair loss, despite no significant difference between those with and without hair loss.
research Preliminary Toxicity Profile of Arotinoids SMR-2 and SMR-6 in Male B6D2F1 Mice
SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe symptoms and organ damage in mice.
research Exogenous testosterone, finasteride and castration effects on testosterone, insulin, zinc and chromium in adult male rats.
Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.
research Knowledge, Attitude, and Practices Related to Vitamin D, Zinc, and Ferritin Deficiencies and the Associated Risk of Hair Loss in Jazan, Saudi Arabia
Most people in Jazan know about vitamin D, zinc, and ferritin's link to hair loss but don't practice enough preventive measures.
research In vitro biotransformation of finasteride in rat hepatic microsomes. Isolation and characterization of metabolites.
research Afamin serum concentrations are associated with insulin resistance and metabolic syndrome in polycystic ovary syndrome
High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.
research Preparation of Finasteride via Oxidative Elimination of 2-Iododihydrofinasteride by Using Peroxydisulfates as Oxidizing Agents
Using K2S2O8 as an oxidizing agent in a specific condition, we can make Finasteride with 96.3% yield and 99.6% purity. This method is also good for other compounds and is environmentally friendly.