Certain medications can negatively impact male fertility.
January 2005 in “Elsevier eBooks” Insulin resistance and hyperinsulinism are linked to fertility issues and can worsen symptoms of PCOS.
January 2022 in “Skin appendage disorders” Finasteride is effective for male hair loss, but it may cause fertility issues, mental health problems, and rarely, breast growth. Regular health checks can reduce the risk of prostate cancer. Patient understanding and involvement in treatment is important.
97 citations
,
March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
1 citations
,
August 2025 in “Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine” BMI should be considered in future research on dutasteride's effects on fertility.
February 2026 in “European Urology”
October 2025 in “Česká gynekologie” Hyperprolactinemia is the most common cause of secondary amenorrhea, followed by drug use.
124 citations
,
July 1997 in “Journal of Biological Chemistry” Overexpressing a specific enzyme in mice causes hair loss and female infertility.
39 citations
,
January 2019 in “The World Journal of Men's Health” Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
11 citations
,
August 2024 in “Advanced Healthcare Materials” A new hydrogel with stem cells can repair damaged uterine lining and improve fertility.
April 2012 in “CORD. Coconut research & development/CORD” Coconut leaf vermiwash improves soil health and crop yields in organic farming.
257 citations
,
July 2018 in “Obstetrics & Gynecology” PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.
222 citations
,
January 2014 in “International journal of reproductive medicine” Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
166 citations
,
October 2018 in “Endocrine Reviews” Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.
117 citations
,
May 2017 in “Human Reproduction Update” The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.
104 citations
,
October 1999 in “The Journal of Urology” Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.
91 citations
,
April 2017 in “Diabetes & Metabolic Syndrome: Clinical Research and Reviews” Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.
88 citations
,
September 2003 in “Clinical endocrinology” Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.
69 citations
,
September 2006 in “Human Reproduction” Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
58 citations
,
December 2018 in “Nature Communications” Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.
47 citations
,
January 2021 in “Fertility and Sterility” COVID-19 might affect male fertility, but more research is needed to understand the full impact.
45 citations
,
March 2015 in “Clinical Endocrinology” Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
38 citations
,
October 2013 in “Gynecologic and Obstetric Investigation” Severe iron deficiency lowers fertility in female rats.
22 citations
,
September 2021 in “Journal of Personalized Medicine” The pandemic worsened physical and mental challenges for women with PCOS.
22 citations
,
October 2017 in “Australian & New Zealand Journal of Obstetrics & Gynaecology” Many young Australian women think they have PCOS, but only a few are diagnosed correctly, causing unnecessary worry.
20 citations
,
June 2012 in “Human Reproduction” Women with polycystic ovarian syndrome are more likely to have cervical insufficiency, especially South Asian and Black women.
20 citations
,
January 2008 in “Reproductive Biomedicine Online” Sexual orientation does not affect the prevalence of PCOS or fertility rates in women undergoing artificial donor insemination.
19 citations
,
February 2023 in “Environmental and experimental botany” Jasmonic acid helps plants grow, defend against threats, and survive stressful conditions like drought and salt.
19 citations
,
April 2020 in “Dermatologic Therapy” Dutasteride works better than finasteride for hair loss, with both being safe to use.
19 citations
,
February 2018 in “International Journal of Endocrinology and Metabolism” The questionnaire is valid and reliable but needs more testing for future predictions.