research External genitalia abnormalities in male rats exposed in utero to finasteride, a 5α-reductase inhibitor
Finasteride exposure in pregnancy causes genital abnormalities in male rats.
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research Human hair follicle: reservoir function and selective targeting
The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
research Effects of EGF on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles
EGF makes hair follicles grow longer but stops hair production.
research A Novel Point Mutation in the Ligand-Binding Domain (LBD) of the Human Glucocorticoid Receptor (hGR) Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus of hGR LBD in Conferring Transactivational Activity
A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.
research GROWTH FACTORS IN HAIR ORGAN DEVELOPMENT AND THE HAIR GROWTH CYCLE
Growth factors are crucial for hair development and could help treat hair diseases.
research Hair cycle-specific expression of versican in human hair follicles
Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.
research Myocardial NF-κB activation is essential for zebrafish heart regeneration
NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.
research Identification of Androgen-Inducible TGF-β1 Derived from Dermal Papilla Cells as a Key Mediator in Androgenetic Alopecia
TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.
research Effect of Minoxidil on Cultured Keratinocytes
Minoxidil helps hair cells live longer and grow longer.
research FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program
The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.
research Direct Effects of Minoxidil on Epidermal Cells in Culture
Minoxidil promotes hair growth by increasing cell division and DNA synthesis.
research The control of hair growth: An overview
Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.
research Dihydrotestosterone Stimulates 5a-Reductase Activity in Pubic Skin Fibroblasts*
Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.
research Reorganization of hair follicles in human skin organ culture induced by cultured human follicle-derived cells
Injected human hair follicle cells can create new, small hair follicles in skin cultures.
research Exogenous IGF-1 promotes hair growth by stimulating cell proliferation and down regulating TGF-β1 in C57BL/6 mice in vivo
IGF-1 injections help mice grow more hair by increasing cell growth and blocking a hair growth inhibitor.
research Morphometric Analysis of the Human Scalp Hair Follicle: Practical Implications for the Hair Transplant Surgeon and Hair Regeneration Studies
The research provides specific measurements for hair follicles that can improve hair transplant and regeneration techniques.
research Skin wounds in the MRL/MPJ mouse heal with scar
MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.
research Analysis of sequential hair segments reflects changes in the metabolome across the trimesters of pregnancy
Hair analysis can reveal metabolic changes and potential pregnancy complications.
research Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction
High levels of androgens during early development may cause PCOS-like symptoms.
research Metabolomic biomarkers in women with polycystic ovary syndrome: a pilot study
Certain metabolites are lower in women with PCOS and could be potential markers for the condition.
research Malignancy and Cancer Treatment-Related Hair and Nail Changes
Hair and nail changes can indicate health issues, including cancer and side effects from cancer treatments.
research Presence of polycystic ovary syndrome is associated with longer anogenital distance in adult Mediterranean women
Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.
research Fibroblast growth factor 5-short (FGF5s) inhibits the activity of FGF5 in primary and secondary hair follicle dermal papilla cells of cashmere goats
FGF5s can block the effects of FGF5, which may help control hair growth in cashmere goats.
research Fructus panax ginseng extract promotes hair regeneration in C57BL/6 mice
Panax ginseng extract helps mice grow hair.
research Which chemicals should be grouped together for mixture risk assessments of male reproductive disorders?
Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.
research CD4+CD25+FoxP3+ Regulatory Tregs inhibit fibrocyte recruitment and fibrosis via suppression of FGF-9 production in the TGF-β1 exposed murine lung
Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.
research Effect of Adenovirus-Mediated Expression of Sonic Hedgehog Gene on Hair Regrowth in Mice With Chemotherapy-Induced Alopecia
Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.
research Reversal of androgenetic alopecia by topical ketoconzole: Relevance of anti-androgenic activity
Ketoconazole lotion can improve hair regrowth for some people with androgenetic alopecia.
research Endogenous human skin equivalent promotes in vitro morphogenesis of follicle-like structures
Endo-HSE helps grow hair-like structures from human skin cells in the lab.
research Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis
Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.