research Mouse models with a disrupted PTHrP gene or a disrupted PTH gene (PTH−/− mice)
PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.
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research Use of chemotherapy during human pregnancy
Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.
research Hirsutism and Virilization in the Female
The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.
research Delayed Puberty
A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.
research Hair Changes Caused by Aging
Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.
research Mixed “Antiandrogenic” Chemicals at Low Individual Doses Produce Reproductive Tract Malformations in the Male Rat
Low doses of mixed chemicals cause permanent reproductive malformations in male rats.
research Chapter 6 Fetal Skin Wound Healing
Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
research Management of acne
Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.
research Hair Growth Induction: Roles of Growth Factors
EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
research Hydrogen peroxide disrupts scarless fetal wound repair
Hydrogen peroxide can cause scars by changing healing processes and increasing certain protein levels.
research Mammalian Fetal Organ Regeneration
Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.
research An overview of zinc and its importance in dermatology-Part II: The association of zinc with some dermatologic disorders
Zinc helps manage skin disorders and deficiencies can worsen some conditions.
research HAIR DISORDERS
The document explains different hair loss types and treatments, emphasizing diagnosis through examination and tests, and specific treatments for each condition.
research Collagen-Heparin-FGF2-VEGF Scaffolds Induce a Regenerative Gene Expression Profile in a Fetal Sheep Wound Model
Collagen-heparin-FGF2-VEGF scaffolds can improve skin healing.
research Alopecia in children
Most hair loss in children is caused by a few common conditions and is easy to diagnose, but rare types require careful evaluation.
research Tissue homeostasis
Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
research Hair Loss in Children, Etiologies, and Treatment
Early treatment of children's hair loss, which can be caused by various factors, is important due to its emotional impact.
research Finasteride, a Type 2 5α-reductase inhibitor, in the treatment of men with androgenetic alopecia
Finasteride effectively treats male hair loss, improving growth and density.
research Management of unwanted hair in females
Different hair removal methods have pros and cons, and more evidence is needed to prove laser treatments work.
research Study on Histamine Related Enzyme Activities during Murine Hair Cycle.
Histamine and its enzyme may help start hair regrowth.
research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: annotated tables
Mutant mice help researchers understand hair growth and related genetic factors.
research The evaluation and management of hirsutism*1
Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.
research Finasteride
Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
research Effects of Flutamide and Finasteride on Rat Testicular Descent
Androgens, like testosterone, are crucial for early testicular descent in rats.
research HAIR REGROWTH
Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.
research 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder
High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
research Molecular epidemiology of hypospadias: Review of genetic and environmental risk factors
Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.
research Neural Mechanisms of Hair Growth Control
Nerves and chemicals in the body can affect hair growth and loss.
research Aging of hair
Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.
research Inhibition of rat α-reductases by finasteride: Evidence for isozyme differences in the mechanism of inhibition
Finasteride effectively blocks rat enzymes, but with varying methods and strength.