72 citations
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October 1998 in “Baillière's clinical endocrinology and metabolism” Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
69 citations
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September 1991 in “Journal of Surgical Research” Understanding how fetal wounds heal could help improve healing in adults.
60 citations
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April 2012 in “Physiology” The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
56 citations
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August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.
55 citations
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March 2000 in “American journal of clinical dermatology” Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
53 citations
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October 1984 in “Endocrine reviews” Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
47 citations
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September 2008 in “British Journal of Dermatology” Ludwig pattern hair loss in women results from varying sensitivity in hair follicles, causing fewer visible hairs.
43 citations
,
October 2019 in “Pediatric Research” Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.
42 citations
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January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
40 citations
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January 2009 in “Skin Pharmacology and Physiology” Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.
30 citations
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April 2007 in “Dermatologic Clinics” The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.
29 citations
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September 2004 in “Fertility and Sterility” Intermittent low-dose finasteride works as well as daily use for treating excessive hair growth in women.
27 citations
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December 2015 in “Mayo Clinic Proceedings” The document concludes that lifestyle changes and medical treatments can significantly reduce symptoms of Hidradenitis Suppurativa, a chronic skin condition.
25 citations
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May 1994 in “Journal of Investigative Dermatology” Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.
24 citations
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October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
23 citations
,
February 2014 in “Journal of Pediatric and Adolescent Gynecology” Low-dose finasteride reduces excessive hair growth in teenage girls safely and affordably.
22 citations
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May 1999 in “International Journal of Dermatology” Hair loss from genetics and hormones can be treated with drugs or surgery.
17 citations
,
June 2017 in “Gene” A rare genetic mutation found in an Indian family can be detected through prenatal screening.
17 citations
,
March 2006 in “Journal of Cosmetic Dermatology” Hormonal changes during and after pregnancy can cause hair growth changes and hair loss, with treatments available for some conditions.
16 citations
,
February 2007 in “Plastic and Reconstructive Surgery” Keratinocytes show more TGF-β system activity and collagen production as they age, which might affect wound scarring.
15 citations
,
March 1997 in “International Journal of Dermatology” Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.
14 citations
,
October 2015 in “PLoS ONE” Keratin 14 is uniquely found in a specific group of placental cells.
14 citations
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November 2008 in “Expert opinion on drug metabolism & toxicology” Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.
9 citations
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January 2017 in “Journal of Clinical and Diagnostic Research” Most pregnant women experience skin changes, mainly increased pigmentation, and some develop pregnancy-related skin conditions and infections.
8 citations
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April 2015 in “Expert Review of Gastroenterology & Hepatology” Effective symptom management in IBD improves quality of life and prevents complications.
7 citations
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October 2015 in “American Journal of Primatology” Monkeys with hair loss during pregnancy showed higher stress hormone levels and invested differently in their offspring.
7 citations
,
September 2013 in “Current Dermatology Reports” Some skin medications are safe for pregnant women, but others pose risks or should not be used.
5 citations
,
May 2017 in “Current Opinion in Pediatrics” Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.
5 citations
,
February 2010 in “Expert Review of Dermatology” Treating both the mind and skin together, especially by managing stress, can greatly improve outcomes for skin disorders linked to psychological issues.
4 citations
,
August 2010 in “Acta Biologica Hungarica” New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.