111 citations
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January 2007 in “Seminars in cell & developmental biology” Hair, teeth, and mammary glands develop similarly at first but use different genes later.
84 citations
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October 2014 in “PLoS Genetics” Wnt signaling is essential for forming the skin's spinous layer through a BMP-FGF pathway.
56 citations
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February 2010 in “PLOS ONE” Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
2 citations
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January 2009 in “Folia Pharmacologica Japonica” The document concludes that more research is needed to create specific drugs for treating male pattern baldness.
223 citations
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January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
160 citations
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January 2014 in “Seminars in cell & developmental biology” Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
149 citations
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July 2017 in “PLoS Biology” Hair follicle patterns form through a mix of self-organization and signaling interactions.
67 citations
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December 2008 in “Developmental Biology” Msx2 and Foxn1 are both crucial for hair growth and health.
50 citations
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April 2014 in “Nature Communications” The research identified new skin traits in mice, some linked to human skin conditions.
39 citations
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September 2011 in “Tissue Engineering Part B-reviews” Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
11 citations
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January 2012 in “Journal of cell science” Rac1 is essential for proper hair structure and color.
29 citations
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March 2019 in “British Journal of Dermatology” Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
417 citations
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September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
24 citations
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October 2017 in “Biomolecules” Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
8 citations
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February 2025 in “Frontiers in Medicine” IGF-1, KGF, and stem cells help skin cells move and survive, potentially speeding up wound healing.
8 citations
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April 2020 in “Journal of Ethnopharmacology” Herbs might help with hair loss, but more research is needed to confirm their safety and effectiveness.
8 citations
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November 2020 in “Frontiers in Cell and Developmental Biology” Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
9 citations
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December 2020 in “International Journal of Medical Sciences” iPSCs help understand and treat neurodevelopmental disorders.
April 2025 in “Scientific Reports” Astragaloside A may help fight lung cancer by targeting specific proteins.
64 citations
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January 2015 in “BioMed Research International” Certain growth factors can promote hair growth in mice by activating hair growth-related proteins.
9 citations
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January 2014 in “Molecular Genetics and Metabolism Reports” The rhg mutation in mice affects the Oat gene, causing hair growth issues and other symptoms.
Lack of Fgf21 slows hair growth by affecting gene interactions.
57 citations
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May 2016 in “Matrix Biology” Laminin α5 is essential for skin communication and health.
39 citations
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November 2007 in “Journal of Histochemistry & Cytochemistry” NG2 is crucial for normal skin and hair development in mice.
50 citations
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September 2012 in “Developmental Biology” Sprouty and FGF balance is crucial for normal feather shape and size.
5 citations
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March 2022 in “Frontiers in Medicine” PRP is effective for treating hair loss, especially with other treatments.
1 citations
,
June 2021 in “Journal of pharmacopuncture” CBD may help restore hair growth-related protein levels in alopecia caused by hormones or other factors.
12 citations
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August 2018 in “BMC Biotechnology” A protein found in safflower seeds can stimulate hair growth and speed up wound healing in mice.
Using Arabidopsis thaliana to produce KGF-2 is a promising, cost-effective method for hair growth and wound healing products.
21 citations
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June 2016 in “PloS one” Zebrafish need MYC and FGF to regenerate inner ear hair cells.