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GlossaryFibroblast Growth Factor 20

protein involved in hair follicle development and cell growth

Fibroblast Growth Factor 20 (FGF20) is a protein that plays a crucial role in cell growth, tissue repair, and development. It is particularly important in the context of hair growth, as it helps regulate the proliferation and differentiation of cells in hair follicles. This makes FGF20 a significant factor in studies related to hair loss and potential treatments for conditions like alopecia.

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Adenosine Stimulates Growth of Dermal Papilla and Lengthens the Anagen Phase by Increasing the Cysteine Level via Fibroblast Growth Factors 2 and 7 in an Organ Culture of Mouse Vibrissae Hair Follicles

research Adenosine stimulates growth of dermal papilla and lengthens the anagen phase by increasing the cysteine level via fibroblast growth factors 2 and 7 in an organ culture of mouse vibrissae hair follicles

28 citations , October 2011 in “International Journal of Molecular Medicine”

Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.

research Enhanced effect of fibroblast growth factor-2-containing dalteparin/protamine nanoparticles on hair growth

19 citations , May 2016 in “Clinical, cosmetic and investigational dermatology”

FGF-2&D/P nanoparticles can help treat hair loss.

research Structure-guided PEGylated fibroblast growth factor 2 variants accelerate wound healing with improved stability

1 citations , May 2020

Compound 6 is a promising candidate for better wound healing.

CRISPR/Cas9-Mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen

research CRISPR/Cas9-mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen

13 citations , March 2020 in “Genes”

Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.

research Suppression of Cutibacterium acnes-Mediated Inflammatory Reactions by Fibroblast Growth Factor 21 in Skin

7 citations , March 2022 in “International Journal of Molecular Sciences”

FGF21 can help reduce skin inflammation caused by C. acnes.

Fibroblast Growth Factors Stimulate Hair Growth Through Beta-Catenin and Shh Expression in C57BL/6 Mice

research Fibroblast Growth Factors Stimulate Hair Growth throughβ-Catenin and Shh Expression in C57BL/6 Mice

64 citations , January 2015 in “BioMed Research International”

Certain growth factors can promote hair growth in mice by activating hair growth-related proteins.

research Growth factor mimetics for skin regeneration: In vitro profiling of primary human fibroblasts and keratinocytes

3 citations , May 2021 in “Archiv der Pharmazie”

SUN11602 and ONO-1301 could help in skin healing and creating artificial skin.

research Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts

9 citations , March 2019 in “Molecular & cellular proteomics”

Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.

research Enriched-GF: A Reproducible High-Yield Autologous Blood-Derived Growth Factor Method for Regenerative Medicine

March 2026 in “bioRxiv (Cold Spring Harbor Laboratory)”

The Enriched-GF method efficiently produces high-yield growth factors for tissue repair.

research 730 M2 macrophages promote wound induced hair neogenesis through the production of growth factors

April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology”

M2 macrophages help hair regrowth in wounds by making growth factors.

research Engineered Nanovesicles from Fibroblasts Modulate Dermal Papillae Cells In Vitro and Promote Human Hair Follicle Growth Ex Vivo

4 citations , December 2022 in “Cells”

Engineered nanovesicles from fibroblasts may help treat hair loss by promoting hair growth.

Hypoxia Treatment of Adipose Mesenchymal Stem Cells Promotes the Growth of Dermal Papilla Cells via HIF-1α and ERK1/2 Signaling Pathways

research Hypoxia Treatment of Adipose Mesenchymal Stem Cells Promotes the Growth of Dermal Papilla Cells via HIF-1α and ERK1/2 Signaling Pathways

1 citations , July 2023 in “International Journal of Molecular Sciences”

Treating fat stem cells with low oxygen boosts hair growth cell growth through specific signaling pathways.

Hair Regenerative Effect of Silk Fibroin Hydrogel with Incorporation of FGF-2-Liposome and Its Potential Mechanism in Mice with Testosterone-Induced Alopecia Areata

research Hair regenerative effect of silk fibroin hydrogel with incorporation of FGF-2-liposome and its potential mechanism in mice with testosterone-induced alopecia areata

12 citations , September 2018 in “Journal of Drug Delivery Science and Technology”

The silk fibroin hydrogel with FGF-2-liposome can potentially treat hair loss in mice.

research miR-129-5p Participates in Hair Follicle Growth by Targeting HOXC13 in Rabbit

5 citations , April 2022 in “Genes”

miR-129-5p affects hair growth by targeting the HOXC13 gene.

research Adipose stem cells from type 2 diabetic mice exhibit therapeutic potential in wound healing

21 citations , July 2020 in “Stem Cell Research & Therapy”

Fat stem cells from diabetic mice can still help heal wounds.

Interleukin-1 and Keratinocyte Growth Factor/Fibroblast Growth Factor-7 Gene Expression in Skin Experimental Irritant Contact Dermatitis Mouse Model Treated with Aqueous Extract of Trachyspermum Copticum Seeds

research Interleukin-1 and Keratinocyte Growth Factor/Fibroblast Growth Factor-7 Gene Expression in Skin Experimental Irritant Contact Dermatitis Mouse Model Treated with Aqueous Extract of Trachyspermum copticum (L.) Link Seeds

August 2018

Ajwain seed extract improved skin healing and hair growth in a mouse skin irritation model.

research Therapeutic Effects of Growth Factor Cocktail Including Fibroblast Growth Factor 9 in Patients with Pattern Hair Loss

September 2017 in “Journal of Clinical Dermatology”

A growth factor cocktail with FGF9 and microneedling effectively increases hair density and diameter in hair loss patients.

research Effect of Fibroblast Growth Factor 10 and an Interacting Non-Coding RNA on Secondary Hair Follicle Dermal Papilla Cells in Cashmere Goats’ Follicle Development Assessed by Whole-Transcriptome Sequencing Technology

2 citations , July 2023 in “Animals”

FGF10 and non-coding RNAs are important for cashmere goat hair follicle development.

research Effect of iontophoresis with growth factor cocktail containing fibroblast growth factor 5-short applied to the scalp in patients with androgenetic alopecia – A split study

January 2020 in “Global dermatology”

Iontophoresis with a growth factor cocktail helps hair growth in patients with androgenetic alopecia.

research Effects Of Keratin-Gelatin And Basic Fibroblast Growth Factor-Gelatin Composite Film On Open Wound Healing In Dogs And Cats

January 2007 in “Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia)”

Keratin-gelatin film improves wound healing in dogs and cats.

Cytokine Loaded Layer-By-Layer Ultrathin Matrices to Deliver Single Dermal Papilla Cells for Spot-By-Spot Hair Follicle Regeneration

research Cytokine loaded layer-by-layer ultrathin matrices to deliver single dermal papilla cells for spot-by-spot hair follicle regeneration

19 citations , December 2015 in “Journal of Materials Chemistry B”

Scientists have created a method to deliver specific cells that can regenerate hair follicles, potentially offering a new treatment for hair loss.

research Effects of Lespedeza Cuneata aqueous extract on testosterone-induced prostatic hyperplasia

16 citations , January 2019 in “Pharmaceutical biology”

Lespedeza cuneata extract may help treat enlarged prostate.

research Influence of Recombinant Codon-Optimized Plasmid DNA Encoding VEGF and FGF2 on Co-Induction of Angiogenesis

15 citations , February 2021 in “Cells”

Transfected cells with VEGF and FGF2 genes improve skin wound healing by enhancing blood flow and regeneration.

research Specific inhibition of FGF5-induced cell proliferation by RNA aptamers

15 citations , February 2021 in “Scientific Reports”

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

research Collagen-Heparin-FGF2-VEGF Scaffolds Induce a Regenerative Gene Expression Profile in a Fetal Sheep Wound Model

9 citations , August 2024 in “Tissue Engineering and Regenerative Medicine”

Collagen-heparin-FGF2-VEGF scaffolds can improve skin healing.

research Hyaluronic acid-FGF2-derived peptide bioconjugates for suppression of FGFR2 and AR simultaneously as an acne antagonist

6 citations , February 2023 in “Journal of nanobiotechnology”

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

research A study of the effects of physical dermabrasion combined with chemical peeling in porcine skin

5 citations , October 2014 in “Journal of cosmetic and laser therapy”

Combining physical dermabrasion with chemical peeling is more effective for skin treatment than chemical peeling alone.

research Kyoh® Rocket Leaf Extract Regulates Proliferation and VEGF and FGF7 Expression in Human Dermal Follicle Papilla Cells

March 2025 in “Molecules”

Kyoh® rocket leaf extract may promote hair growth naturally with fewer side effects.

research Seasonal Gene Expression Profile Responsible for Hair Follicle Development in Angora Goats

January 2023 in “Kafkas üniversitesi veteriner fakültesi dergisi/Kafkas üniversitesi veteriner fakültesi dergisi”

Seasonal changes affect gene activity linked to hair growth in Angora goats.

Comparative Transcriptome Profiling of Hair Follicles from Forest Musk Deer at Different Stages

research Comparative transcriptome profiling of hair follicles from forest musk deer (Moschus berezovskii) at different stages

November 2022 in “Research Square (Research Square)”

The research provides insights into hair follicle growth in forest musk deer by identifying key genes and pathways involved.