January 2026 in “Burns & Trauma” NLRP3 helps control inflammation and repair in wound healing, making it a potential target for treatment.
December 2025 in “Advanced Healthcare Materials” The Spherical Skin Model improves drug and cosmetic testing by accurately mimicking human skin for efficient compound screening.
March 2025 in “Tissue and Cell” Frozen-thawed fibroblast sheets enhance wound healing and hair growth in mice.
January 2025 in “Open Life Sciences” Overexpression of the HE4 gene in mice causes eye inflammation and cloudiness.
The Chromolaena odorata patch significantly speeds up wound healing.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Aged individuals heal wounds less effectively due to specific immune cell issues.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Adipocytes can change into fibroblast-like cells to help with wound healing.
January 2023 in “Open veterinary journal” Cow blood vessel cell secretions helped heal rat burn wounds and may treat burns and hair loss.
June 2020 in “Journal of Investigative Dermatology” Certain bacteria can enhance skin regeneration.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” miR-486 may help prevent hair loss in alopecia areata.
September 2017 in “Journal of Investigative Dermatology” The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.
October 2013 in “Journal of Investigative Dermatology” Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.
February 2026 in “Plastic and Aesthetic Research” Regenerative aesthetic medicine aims to restore tissue function, but needs more consistent evidence and standardized practices.
January 2020 in “Global dermatology” Iontophoresis with a growth factor cocktail helps hair growth in patients with androgenetic alopecia.
148 citations
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December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
126 citations
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August 2018 in “Molecular Systems Biology” Fibroblast state switching is crucial for skin healing and development.
86 citations
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June 2017 in “Stem cell investigation” Stem cells from hair follicles can safely treat hair loss.
74 citations
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August 2023 in “Frontiers in Immunology” Fibroblasts are key to wound healing by managing immune cells and forming scar tissue.
56 citations
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March 2015 in “Cell death and differentiation” Older skin has higher cancer risk due to inflammation and stem cell issues.
27 citations
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January 2012 in “Current Topics in Microbiology and Immunology” Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
10 citations
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March 1990 in “The Journal of Dermatology” Long-term etretinate use may cause delayed wound healing and extra tissue growth after injury.
9 citations
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July 2018 in “Current Pharmaceutical Design” HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
5 citations
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December 2021 in “Journal of Investigative Dermatology” Hedgehog signaling in certain cells is crucial for hair growth during wound healing.
January 2026 in “BioScience Trends” UV radiation causes skin aging by damaging cells and triggering harmful processes.
February 2024 in “Frontiers in physiology” Modifying certain signals in the body can help wounds heal without scars and regrow hair.
August 2022 in “Research Square (Research Square)” Implanted special stem cells from hair follicles helped heal wounds faster and with less scarring in mice.
April 2019 in “Journal of Investigative Dermatology” Eating grape powder may reduce the severity of skin allergy symptoms.
1 citations
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August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
162 citations
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July 2011 in “Biomacromolecules” Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.
62 citations
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July 1993 in “Journal of Investigative Dermatology” Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.