277 citations
,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
178 citations
,
August 2016 in “Advances in wound care” New effective scar treatments are urgently needed due to the current options' limited success.
162 citations
,
July 2011 in “Biomacromolecules” Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.
154 citations
,
November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
137 citations
,
June 2005 in “Climacteric” Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.
120 citations
,
July 2005 in “Dermatologic surgery” Niacinamide improves aging skin and is safe for use in cosmetics.
77 citations
,
July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.
33 citations
,
January 2021 in “Aesthetic Surgery Journal” Low-Level Light Therapy (LLLT) is a safe and effective method for skin rejuvenation, acne treatment, wound healing, body contouring, and hair growth, but more well-designed trials are needed for confirmation.
27 citations
,
July 2017 in “Facial Plastic Surgery” Platelet-Rich Plasma (PRP) shows promise for hair growth and skin improvement in aesthetic surgery.
27 citations
,
September 2015 in “PharmaNutrition” Astaxanthin is a safe antioxidant that may improve heart, skin, eye health, and physical performance, and help manage chronic diseases.
22 citations
,
January 2017 in “Advanced Healthcare Materials” The hydrogels help harvest cells while preserving their mechanical memory, which could improve wound healing.
20 citations
,
December 2015 in “Journal of Pharmacopuncture” Thread-embedding therapy helped hair grow back in mice and might do the same in humans.
20 citations
,
October 2018 in “Aesthetic Plastic Surgery” PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.
19 citations
,
February 2022 in “Journal of Investigative Dermatology” Mechanical stretching can improve or hinder skin regeneration depending on duration.
18 citations
,
January 2022 in “Oxidative Medicine and Cellular Longevity” Fibroblasts are crucial in scar formation and wound healing, with potential therapies aiming for scarless healing.
14 citations
,
January 2020 in “Evidence-based Complementary and Alternative Medicine” A peptide from fermented Trapa japonica fruit may help reduce skin aging.
13 citations
,
March 2013 in “International Journal of Cosmetic Science” AcSDKP may help prevent skin and hair aging and promote their growth.
7 citations
,
January 2021 in “Evidence-based complementary and alternative medicine” Porphyra-334 may help reduce wrinkles and promote hair growth.
6 citations
,
June 2021 in “Developmental biology” Dermal EZH2 controls skin cell development and hair growth in mice.
4 citations
,
October 2025 in “International Journal of Medical Sciences” Tripeptides help heal wounds and regenerate skin by speeding up tissue repair and reducing inflammation.
4 citations
,
November 2014 The skin protects the body, regulates temperature, senses touch, and makes vitamin D.
3 citations
,
October 2023 in “Frontiers in physiology” ceRNA networks offer potential treatments for skin aging and wound healing.
3 citations
,
January 2012 in “Elsevier eBooks” Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.
1 citations
,
May 2026 in “Nature Communications” CD19-CAR T cell therapy may help regenerate skin in systemic sclerosis.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” The plant combination effectively repairs skin and delays aging.
February 2026 in “American Journal of Clinical Dermatology” Radiotherapy can cause skin fibrosis, which is often overlooked and needs better treatment and evaluation.
January 2026 in “RSC Advances” The hydrogel helps heal wounds without scars by releasing two drugs gradually.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Dermal EZH2 controls skin cell growth and differentiation in mice.
March 2026 in “Food, Nutrition and Health.” Collagen peptides may help reduce skin aging by improving elasticity and hydration.
October 2025 in “Cell Proliferation” IL10_ApoEVs improve skin healing and reduce scarring.