238 citations
,
March 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
32 citations
,
February 2024 in “The Journal of Experimental Medicine” CXCL12+ fibroblasts help recruit neutrophils to fight skin infections.
3 citations
,
August 2024 Deep skin fibroblasts help recruit immune cells for better wound healing.
39 citations
,
May 2014 in “Frontiers in Pharmacology” Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.
6 citations
,
December 2022 in “Colloids and Surfaces B: Biointerfaces” The new wound dressing promotes cell growth and healing, absorbs wound fluids well, and is biocompatible.
January 2026 in “Chemical Engineering Journal” Engineered nanovesicles from hair follicle stem cells enable scarless healing of infected wounds.
January 2026 in “Burns & Trauma” NLRP3 helps control inflammation and repair in wound healing, making it a potential target for treatment.
6 citations
,
December 2024 in “F1000Research” Fibroblast and immune cell interactions affect tissue repair and fibrosis.
9 citations
,
June 2020 in “Cell stem cell” Skinny fat cells help wounds heal faster by releasing fatty acids.
1 citations
,
March 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Biodegradable scaffolds help regenerate wounds and hair by activating the immune system.
July 2025 in “Advanced Science” Collagen VI and Semaphorin 3C are important for hair pigmentation and could help treat pigmentation disorders.
November 2024 in “Journal of Investigative Dermatology” Red ginseng components help prevent skin aging by reducing inflammation and improving cell function.
Adipocytes in atopic dermatitis skin change and worsen inflammation and fibrosis.
PDGF signaling is crucial for cell development, wound healing, and fluid regulation in the body.
26 citations
,
December 2019 in “Stem Cell Reports” Proper tissue repair in adult skin requires specific histone hypomethylation.
April 2026 in “Amino Acids” Polyamines are crucial for skin tumor development, and inhibiting them can prevent tumors.
35 citations
,
August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
March 2024 in “Frontiers in genetics” Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.
299 citations
,
January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
119 citations
,
November 2014 in “Trends in Cell Biology” Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.
115 citations
,
February 2016 in “Nature Communications” Epidermal β-catenin activation changes the dermis by signaling different fibroblast types.
48 citations
,
June 2020 in “Current Rheumatology Reports” Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
9 citations
,
May 2021 in “Immunological Reviews” Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
The skin can still regenerate and function well even with fewer fibroblasts.
248 citations
,
November 2011 in “The EMBO Journal” Wnt1/βcatenin signaling is crucial for heart repair after injury.
112 citations
,
May 2020 in “Nature Communications” Adult fibroblasts help heart cells mature and improve heart function.
87 citations
,
January 2016 in “Development” Blocking β-catenin in skin cells improves hair growth during wound healing.
49 citations
,
January 2018 in “Theranostics” The new skin patch with human matrix and antibiotic improves wound healing.
14 citations
,
December 2020 in “Journal of Investigative Dermatology” Aging causes changes in the scalp that can affect hair growth and lead to older-looking hair in women.
June 2021 in “Journal of Cosmetic Dermatology” Laser treatment shows promise for hair growth, but needs further research.