research Stepwise acquisition of unique epigenetic signatures during differentiation of tissue Treg cells
Tissue environment greatly affects the unique epigenetic makeup of regulatory T cells, which could impact autoimmune disease treatment.
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900-930 / 1000+ results research 569 Application of 3D scaffold free dermal spheroids to investigate retinol and retinol alternatives mechanism of action on extracellular matrix
research Retinoids in scarless skin regeneration: from molecular mechanisms to therapeutic strategies
Retinoic acid may help heal skin without scars by reducing fibrosis and supporting skin regeneration.
research Frontal fibrosing alopecia: demographic and clinical characteristics of 490 cases
Frontal fibrosing alopecia mainly affects postmenopausal women and may be linked to thyroid hormones.
research TGF‐β and HSP70 profiles during transformation of yak hair follicles from the anagen to catagen stage
TGF-β2 helps yak hair follicles enter the regression phase, while HSP70 tries to prevent it.
research Proinflammatory cytokines regulate epidermal stem cells in wound epithelialization
Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
research Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model
Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.
research LB789 Novel IFNγ aptamer TAGX-0003 protected hair follicles from immune privilege collapse and reversed Alopecia Areata like phenotype in humanized mouse model
TAGX-0003 protected hair follicles and reversed alopecia areata in a mouse model.
research Bioactive antiinflammatory antibacterial hemostatic citrate-based dressing with macrophage polarization regulation for accelerating wound healing and hair follicle neogenesis
A special dressing called FEA-PCEI can speed up wound healing, reduce scars, and help grow new hair follicles, but only at the right dosage.
research Delayed granulomatous eruption of the nose associated with ruxolitinib
Ruxolitinib can cause a delayed skin reaction on the nose.
research JAK-inhibitors. New players in the field of immune-mediated diseases, beyond rheumatoid arthritis
JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.
research Flightless I exacerbation of inflammatory responses contributes to increased colonic damage in a mouse model of dextran sulphate sodium-induced ulcerative colitis
High levels of the protein Flightless I worsen ulcerative colitis symptoms in mice.
research A woman with iatrogenic androgenetic alopecia responding to finasteride
EF and PXE not closely related.
research Microneedle-AssistedPenetration of Fibronectin Nanogelsfor Enhanced Anti-Aging Healthcare and Diabetic Wound Healing
Fibronectin nanogel microneedles improve skin health and wound healing.
research Frontal fibrosing alopecia treatment options
Combination therapy, especially with finasteride, is effective for treating frontal fibrosing alopecia.
research SOX9 as a key regulator of tissue remodelling and epithelial cell fate transitions.
SOX9 is crucial for cell development and repair but can cause fibrosis and cancer if misregulated.
research Skin metabolism in obesity: A narrative review
Obesity harms skin health by causing inflammation and delayed wound healing.
research Tissue Mechanics in Haired Murine Skin: Potential Implications for Skin Aging
Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
research 020 Sphingosine 1-phosphate receptor signalling promotes hair growth and inhibits perifollicular T-cell expansion and immune privilege collapse ex vivo
research Madarosis and facial keratinaceous spines
Reducing immunosuppression and using antiviral creams improved the woman's skin condition.
research Ruxolitinib Rescues Multiorgan Clinical Autoimmunity in Patients with APS-1
Ruxolitinib significantly improves multiple autoimmune conditions in APS-1 patients.
research The usefulness of trichoscopy in the diagnosing of fibrosing alopecia in pattern distribution
Trichoscopy is crucial for accurately diagnosing fibrosing alopecia in pattern distribution.
research Decision letter: Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells
IL-1 signaling is crucial for hair follicle stem cell growth and wound healing.
research Novel skin patch combining human fibroblast-derived matrix and ciprofloxacin for infected wound healing
The new skin patch with human matrix and antibiotic improves wound healing.
research Translational Positioning of Janus Kinase (JAK) Inhibitors in Alopecia Areata
JAK inhibitors may help treat Alopecia Areata but need careful monitoring due to side effects.
research 768 Dermal fibroblast expression of lef1 is critical to normal skin and hair development and regenerative wound healing in mice
Lef1 is essential for normal skin, hair growth, and healing wounds in mice.
research Efficacy of adipose stromal cells-enriched high-density fat graft combined with BTX-A for Raynaud’s phenomenon: a prospective cohort study
Combining fat grafts with botulinum toxin helps improve Raynaud's symptoms.
research Sustaining treatment response in alopecia areata through tofacitinib dose tapering: A single-center retrospective study
research Successful Treatment of Refractory Alopecia Areata Universalis and Psoriatic Arthritis, But Not of Plaque Psoriasis with Tofacitinib in a Young Woman
Tofacitinib helped a young woman's severe hair loss and arthritis but not her plaque psoriasis.
research Correlation of clinical and trichoscopy features with the degree of histologic inflammation in lichen planopilaris and frontal fibrosing alopecia in a cross-sectional study
Clinical signs don't match inflammation levels in lichen planopilaris and frontal fibrosing alopecia.