89 citations
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November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
85 citations
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December 2017 in “Developmental Biology” Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
77 citations
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August 2025 in “Signal Transduction and Targeted Therapy” Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.
62 citations
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March 2012 in “Journal of the European Academy of Dermatology and Venereology” Using dermoscopy to guide scalp biopsies is an effective way to diagnose cicatricial alopecia.
57 citations
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March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
53 citations
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April 2021 in “Cell Host & Microbe” Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.
49 citations
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October 2014 in “International Scholarly Research Notices” Eclipta alba has many health benefits and contains compounds with potential for drug development.
47 citations
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November 2012 in “Wound repair and regeneration” Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
46 citations
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August 2019 in “Journal of Ethnopharmacology” Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.
44 citations
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November 1998 in “Australasian Journal of Dermatology” Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.
40 citations
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May 2012 in “British Journal of Dermatology” Recognizing specific features of African-American hair can help diagnose hair loss conditions.
36 citations
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August 2021 in “Nature Cell Biology” Organoids can help study COVID-19 and develop treatments, but face challenges like instability and limited renewal.
35 citations
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August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
33 citations
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January 2018 in “The International Journal of Developmental Biology” Cell aging can be both good and bad for tissue repair.
31 citations
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June 2017 in “Regeneration” BMP2 needs periosteal tissue to help regenerate mouse middle finger bones within a specific time.
30 citations
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December 2018 in “Trends in Endocrinology and Metabolism” Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.
30 citations
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March 2015 in “Journal of Dermatology” Hair thickness differences help diagnose hair loss severity.
30 citations
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May 2014 in “American Journal of Clinical Dermatology” The conclusion is that better understanding and more research are needed to effectively manage follicular and scarring disorders in skin of color, with an emphasis on patient education and cultural awareness.
24 citations
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January 2011 in “International Journal of Trichology” Light microscopy is useful for diagnosing different hair disorders.
19 citations
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January 1997 in “Dermatologic Clinics” Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.
19 citations
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January 1987 in “Dermatology” Minoxidil slows down skin cell growth and may help treat scars and skin conditions.
17 citations
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June 2018 in “Frontiers in Physiology” ADM scaffolds help skin heal by promoting a healing-type immune response.
16 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.
15 citations
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January 2015 in “Skin Pharmacology and Physiology” Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.
14 citations
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February 2020 in “Scientific reports” Telocytes in the scalp may help with skin regeneration and maintenance.
14 citations
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January 2020 in “Biomaterials Science” Created microspheres show potential for safe and effective use in prostate artery embolization.
12 citations
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September 2021 in “The International Journal of Developmental Biology” Liposomal carriers can improve tissue regeneration by stabilizing and retaining growth factors.
11 citations
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August 2017 in “Journal of Chromatographic Science” The new method is rapid, sensitive, and accurate for evaluating the quality of the medicinal herb Platycladi cacumen.
11 citations
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April 2016 in “The American Journal of Dermatopathology” Special and immunohistochemical stains are not routinely needed for diagnosing hair disorders.
10 citations
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October 2020 in “Frontiers in Cell and Developmental Biology” Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.